SCHEMBL3277627

SCHEMBL3277627

C=C(c1ccc(OC)cc1)c1ccc(OC)cc1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 3/20 0.59
CES2 O00748 2/20 0.58
CES1 P23141 2/20 0.58
CA1 P00915 5/20 0.58
CA2 P00918 5/20 0.58
CA12 O43570 1/20 0.58
CA7 P43166 1/20 0.58
CA9 Q16790 1/20 0.58
CA14 Q9ULX7 1/20 0.58
ALDH1A1 P00352 3/20 0.54
SMN1; SMN2 Q16637 2/20 0.54
NR1I2 O75469 1/20 0.54
PRSS1 P07477 1/20 0.54
PRSS2 P07478 1/20 0.54
PRSS3 P35030 1/20 0.54
PARP1 P09874 1/20 0.54
PARP10 Q53GL7 1/20 0.54
PARP2 Q9UGN5 1/20 0.54
PARP4 Q9UKK3 1/20 0.54
KDM4E B2RXH2 2/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15232917 0.93 PDE4A (0.56) MAPTCES2CES1CA1CA2
SCHEMBL10679674 0.93 PARP10 (0.59) MAPTCES2CES1CA1CA2
SCHEMBL18346348 0.91 CES2 (0.64) MAPTCES2CES1CA1CA2
SCHEMBL21220132 0.91 CES2 (0.64) MAPTCES2CES1CA1CA2
SCHEMBL2008961 0.91 CES2 (0.64) MAPTCES2CES1CA1CA2
SCHEMBL14264170 0.91 ACHE (0.65) MAPTCES2CES1CA1CA2
SCHEMBL6339597 0.89 MAPT (0.66) MAPTCES2CES1CA1CA2
SCHEMBL14335633 0.89 APP (0.51) MAPTCES2CES1CA1CA2
SCHEMBL16607610 0.85 ACHE (0.58) MAPTCES2CES1CA1CA2
SCHEMBL10685576 0.85 NPC1 (0.57) MAPTALDH1A1SMN1; SMN2NR1I2PRSS1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 91 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4187105-A Photosensitive image forming composition containing at least one substituted bis-diaryl vinylidene compound and/or at least one substituted bis-diaryl imine compound HORIZONS RESEARCH INCORPORATED (US) 1980-02-05 US claimed
CN-117551023-A Preparation method and application of N-thio-phenyl phthalimide compound 太原理工大学 2024-02-13 CN disclosed
CN-117447370-A Preparation method of aggregation-induced emission material tetraaryl divinyl sulfide 山西蓬勃健康科技有限公司 2024-01-26 CN disclosed
CN-114671850-B Preparation method of conjugated diene compound 兰州大学 2023-05-26 CN disclosed
WO-2023006097-A1 BIFUNCTIONAL CHIMERIC HETEROCYCLIC COMPOUND AND USE THEREOF AS ANDROGEN RECEPTOR DEGRADER 海创药业股份有限公司 2023-02-02 WO disclosed
CN-114671850-A Preparation method of conjugated diene compound 兰州大学 2022-06-28 CN disclosed
CN-109265311-B Phenyl fluorene derivative and preparation method and application thereof 上海兆维科技发展有限公司 2021-06-04 CN disclosed
CN-112608222-A Method for preparing aldehyde ketone compound by olefin oxidation 三峡大学 2021-04-06 CN disclosed
CN-109758438-A The purposes and preparation method of pinosylvin 南通大学 2019-05-17 CN disclosed
CN-108623425-A Method for constructing four-membered ring by visible light catalysis [2+2] reaction 中国科学院理化技术研究所 2018-10-09 CN disclosed
US-4931337-A CONTAINING ORGANIC MATERIAL, ADHESIVE CANON KABUSHIKI KAISHA (JP) 1990-06-05 US disclosed
US-4879315-A Cyclopropyl analogs as anti-estrogenic, anti-tumor and female fertility agents THE BOARD OF REGENTS FOR THE UNIVERSITY OF OKLAHOMA (US) 1989-11-07 US disclosed
US-4770973-A READABLE BY OPTICAL DEVICES AND FIXED BY LIGHT Kanzaki Paper Manufacturing Limited (JP) 1988-09-13 US disclosed
EP-0278763-A2 Information recording medium CANON KABUSHIKI KAISHA (JP) 1988-08-17 EP disclosed
EP-0264198-A2 Optical information recording medium CANON KABUSHIKI KAISHA (JP) 1988-04-20 EP disclosed
EP-0099552-B1 ELECTROPHOTOGRAPHIC PLATE MITSUBISHI KASEI CORPORATION (JP) 1986-10-08 EP disclosed
US-4485160-A INORGANIC PARTICLES, SENSITIZING DYES AND ELECTRON-ATTRACTING COMPOUNDS MITSUBISHI CHEMICAL INDUSTRIES LIMITED (JP) 1984-11-27 US disclosed
EP-0099552-A2 Electrophotographic plate MITSUBISHI KASEI CORPORATION (JP) 1984-02-01 EP disclosed
US-4187105-A Photosensitive image forming composition containing at least one substituted bis-diaryl vinylidene compound and/or at least one substituted bis-diaryl imine compound HORIZONS RESEARCH INCORPORATED (US) 1980-02-05 US disclosed
US-3962356-A INSECTICIDES MONSANTO CHEMICALS LIMITED (AU) 1976-06-08 US disclosed