Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSB | P07858 | 1/20 | 0.55 |
| ▸ | CTSS | P25774 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3277879 | 0.85 | CTSB (0.69) | CTSBCTSS | |
| SCHEMBL13385474 | 0.84 | CTSB (0.71) | CTSBCTSS | |
| SCHEMBL8244871 | 0.84 | CTSB (0.71) | CTSBCTSS | |
| SCHEMBL8248465 | 0.81 | CTSB (0.67) | CTSBCTSS | |
| SCHEMBL4594130 | 0.80 | CTSB (0.39) | CTSB | |
| SCHEMBL13385475 | 0.79 | CTSB (0.88) | CTSBCTSS | |
| SCHEMBL8284369 | 0.78 | CTSB (0.72) | CTSBCTSS | |
| SCHEMBL6369435 | 0.77 | CTSB (0.44) | CTSB | |
| SCHEMBL19093889 | 0.76 | CTSB (0.81) | CTSBCTSS | |
| SCHEMBL12017053 | 0.76 | CTSB (0.81) | CTSBCTSS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7700552-B2 | Macrocyclic inhibitors of hepatitis C virus | MEDIVIR AB (SE) | 2010-04-20 | — | — | US | disclosed |
| US-20090023758-A1 | Macrocyclic Inhibitors of Hepatitis C Virus | MEDIVIR AB (SE) | 2009-01-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090023758-A1 | Macrocyclic Inhibitors of Hepatitis C Virus | CTRC, NOX3, HAVCR2 | CTSB 404/4885CTSS 142/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.