Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 5/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.42 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | APEX1 | P27695 | 1/20 | 0.40 |
| ▸ | GMNN | O75496 | 1/20 | 0.40 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.40 |
| ▸ | TFPI2 | P48307 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.40 |
| ▸ | THPO | P40225 | 1/20 | 0.40 |
| ▸ | GRM2 | Q14416 | 4/20 | 0.38 |
| ▸ | GRM3 | Q14832 | 4/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | SLC1A2 | P43004 | 2/20 | 0.36 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.36 |
| ▸ | PPP5C | P53041 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19285911 | 0.90 | POLB (0.39) | POLBTDP1CTDSP1KDM4ELMNA | |
| SCHEMBL430822 | 0.82 | POLB (0.48) | POLBTDP1CTDSP1KDM4ELMNA | |
| SCHEMBL15646255 | 0.79 | POLB (0.46) | POLBTDP1CTDSP1KDM4ELMNA | |
| SCHEMBL25472592 | 0.79 | POLB (0.39) | POLBTDP1CTDSP1KDM4ELMNA | |
| SCHEMBL24197654 | 0.79 | POLB (0.39) | POLBTDP1CTDSP1KDM4ELMNA | |
| SCHEMBL19688947 | 0.79 | POLB (0.31) | POLBTDP1CTDSP1KDM4ELMNA | |
| SCHEMBL12763440 | 0.78 | POLB (0.48) | POLBTDP1CTDSP1KDM4ELMNA | |
| SCHEMBL12231001 | 0.76 | POLB (0.48) | POLBTDP1CTDSP1KDM4ELMNA | |
| SCHEMBL14972663 | 0.74 | POLB (0.42) | POLBTDP1CTDSP1KDM4ELMNA | |
| SCHEMBL10066840 | 0.72 | POLB (0.38) | POLBTDP1CTDSP1KDM4ELMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7700802-B2 | by utilizing the difference in solubility between a neutralized salt of the endo isomer and a neutral salt of the exo isomer of a dicarboxylic acid having a norbornene or norbornane structure; mixing the above endo and exo mixture with NaOH and a solvent, filtering to separate liquid and solid phase | HITACHI CHEMICAL CO., LTD. (JP) | 2010-04-20 | — | — | US | disclosed |
| US-20070142668-A1 | Method of separating stereoisomers of dicarboxylic acid having norbornene or norbornane structure, or derivative thereof | HITACHI CHEMICAL CO., LTD. (JP) | 2007-06-21 | — | — | US | disclosed |
| EP-1669342-A1 | METHOD OF SEPARATING STEREOISOMERS OF NORBORNENE, DICARBOXYLIC ACID HAVING NORBORNANE STRUCTURE, OR DERIVATIVE THEREOF | Hitachi Chemical Co., Ltd. (JP) | 2006-06-14 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070142668-A1 | Method of separating stereoisomers of dicarboxylic acid having norbornene or norbornane structure, or derivative thereof | EXOC1, RER1, PRMT8 | POLB 2359/4885TDP1 1005/4885CTDSP1 1201/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.