Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 11/20 | 0.61 |
| ▸ | ADRA1A | P35348 | 3/20 | 0.53 |
| ▸ | HTR1A | P08908 | 3/20 | 0.52 |
| ▸ | HTR2A | P28223 | 3/20 | 0.52 |
| ▸ | HTR2C | P28335 | 3/20 | 0.52 |
| ▸ | HRH1 | P35367 | 3/20 | 0.52 |
| ▸ | DRD3 | P35462 | 3/20 | 0.52 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.52 |
| ▸ | ADRA2B | P18089 | 2/20 | 0.52 |
| ▸ | ADRA2C | P18825 | 2/20 | 0.52 |
| ▸ | DRD4 | P21917 | 2/20 | 0.52 |
| ▸ | ADRA1B | P35368 | 2/20 | 0.52 |
| ▸ | HTR7 | P34969 | 2/20 | 0.51 |
| ▸ | HTR2B | P41595 | 2/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | CACNA1F | O60840 | 1/20 | 0.51 |
| ▸ | KCNK2 | O95069 | 1/20 | 0.51 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.51 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9050736 | 0.76 | DRD2 (1.00) | DRD2ADRA1AHTR1AHTR2AHTR2C | |
| SCHEMBL8986058 | 0.72 | DRD2 (0.70) | DRD2ADRA1AHTR1AHTR2AHTR2C | |
| SCHEMBL9051399 | 0.71 | DRD2 (0.80) | DRD2ADRA1AHTR1AHTR2AHTR2C | |
| SCHEMBL11794402 | 0.71 | DRD2 (0.69) | DRD2ADRA1AHTR1AHTR2AHTR2C | |
| SCHEMBL8986040 | 0.70 | DRD2 (0.87) | DRD2ADRA1AHTR1AHTR2AHTR2C | |
| Haloperidol SCHEMBL4113148 | 0.69 | DRD2 (0.83) | DRD2ADRA1AHTR1AHTR2AHTR2C | |
| Chlorohaloperidol SCHEMBL4112719 | 0.69 | DRD2 (1.00) | DRD2ADRA1AHTR1AHTR2AHTR2C | |
| SCHEMBL8967710 | 0.69 | KMT2A (0.66) | DRD2ADRA1AHTR1AHTR2AHTR2C | |
| SCHEMBL3122836 | 0.68 | DRD2 (1.00) | DRD2ADRA1AHTR1AHTR2AHTR2C | |
| SCHEMBL8986015 | 0.68 | DRD2 (0.82) | DRD2ADRA1AHTR1AHTR2AHTR2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7700587-B2 | Haloperidol analogs | FLORIDA A&M UNIVERSITY (US) | 2010-04-20 | — | — | US | disclosed |
| US-20060052363-A1 | which are incapable of metabolizing to BCPP+ like species, and have affinity for D2 receptor subtype and functions as dopamine receptor antagonist | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2006-03-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060052363-A1 | which are incapable of metabolizing to BCPP+ like species, and have affinity for D2 receptor subtype and functions as dopamine receptor antagonist | DBH, TACR1, PRLHR | DRD2 7/4885ADRA1A 564/4885HTR1A 231/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.