Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 18/20 | 0.80 |
| ▸ | HRH1 | P35367 | 11/20 | 0.80 |
| ▸ | DRD3 | P35462 | 11/20 | 0.80 |
| ▸ | HTR1A | P08908 | 10/20 | 0.80 |
| ▸ | HTR2A | P28223 | 8/20 | 0.80 |
| ▸ | DRD4 | P21917 | 7/20 | 0.80 |
| ▸ | HTR2C | P28335 | 4/20 | 0.80 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.80 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.80 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.80 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.80 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.80 |
| ▸ | SLC6A4 | P31645 | 6/20 | 0.62 |
| ▸ | HTR7 | P34969 | 6/20 | 0.62 |
| ▸ | HTR2B | P41595 | 6/20 | 0.62 |
| ▸ | SLC6A3 | Q01959 | 4/20 | 0.57 |
| ▸ | TMEM97 | Q5BJF2 | 4/20 | 0.57 |
| ▸ | SIGMAR1 | Q99720 | 4/20 | 0.57 |
| ▸ | SLC6A2 | P23975 | 3/20 | 0.57 |
| ▸ | DRD1 | P21728 | 2/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9050578 | 0.89 | DRD2 (1.00) | DRD2HRH1DRD3HTR1AHTR2A | |
| SCHEMBL9052209 | 0.80 | DRD2 (0.64) | DRD2HRH1DRD3HTR1AHTR2A | |
| SCHEMBL9050736 | 0.78 | DRD2 (1.00) | DRD2HRH1DRD3HTR1AHTR2A | |
| SCHEMBL9911015 | 0.76 | DRD2 (0.76) | DRD2HRH1DRD3HTR1AHTR2A | |
| SCHEMBL9053117 | 0.73 | DRD2 (0.77) | DRD2HRH1DRD3HTR1AHTR2A | |
| SCHEMBL9051391 | 0.73 | DRD2 (0.58) | DRD2HRH1DRD3HTR1AHTR2A | |
| SCHEMBL8986040 | 0.72 | DRD2 (0.87) | DRD2HRH1DRD3HTR1AHTR2A | |
| SCHEMBL8986015 | 0.72 | DRD2 (0.82) | DRD2HRH1DRD3HTR1AHTR2A | |
| SCHEMBL3278959 | 0.71 | DRD2 (0.61) | DRD2HRH1DRD3HTR1AHTR2A | |
| Chlorohaloperidol SCHEMBL4112719 | 0.71 | DRD2 (1.00) | DRD2HRH1DRD3HTR1AHTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1996002250-A1 | HALOPERIDOL ANALOGS AND THE USE THEREOF | ACEA PHARMACEUTICALS INC. (US) | 1996-02-01 | — | — | WO | disclosed |