⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19640340 | 0.81 | TAAR1 (0.42) | — | |
| SCHEMBL1337579 | 0.81 | MEN1 (0.40) | — | |
| SCHEMBL8790729 | 0.76 | MGLL (0.40) | — | |
| SCHEMBL2643295 | 0.75 | — | — | |
| SCHEMBL1607399 | 0.75 | — | — | |
| SCHEMBL3284545 | 0.75 | — | — | |
| SCHEMBL2642924 | 0.75 | — | — | |
| SCHEMBL9819410 | 0.75 | HTR2A (0.35) | — | |
| SCHEMBL7188782 | 0.75 | ACP3 (0.34) | — | |
| SCHEMBL5542316 | 0.73 | CALM1 (0.57) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 53 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113105425-B | Anti-inflammatory compound, preparation method and anti-inflammatory application thereof | 东北大学 | 2022-07-01 | — | — | CN | claimed |
| CN-113105425-A | Anti-inflammatory compound, preparation method and anti-inflammatory application thereof | 东北大学 | 2021-07-13 | — | — | CN | claimed |
| US-20040044048-A1 | (R)-chiral halogenated 1-substitutedamino-(n+1)-alkanols useful for inhibiting cholesteryl ester transfer protein activity | G.D. SEARLE & CO. (US) | 2004-03-04 | — | — | US | claimed |
| US-20030191306-A1 | Substituted N-Aliphatic-N-Aromatictertiary-Heteroalkylamines useful for inhibiting cholesteryl ester transfer protein activity | G.D. SEARLE & CO. (US) | 2003-10-09 | — | — | US | claimed |
| US-6544974-B2 | Treating atherosclerosis and other coronary artery diseases. | G.D. SEARLE & CO. | 2003-04-08 | — | — | US | claimed |
| US-6521607-B1 | Preventing coronary artery disease | PHARMACIA CORPORATION | 2003-02-18 | — | — | US | claimed |
| US-6476057-B1 | ANTICHOLESTEROL AGENTS; ANTILIPEMIC AGENTS; CARDIOVASCULAR DISORDERS | G.D. SEARLE & CO. | 2002-11-05 | — | — | US | claimed |
| US-6458849-B1 | METHOD OF TREATING OR PREVENTING A CEIP-MEDIATED DISORDER IN A SUBJECT BY ADMINISTERING A THERAPEUTICALLY EFFECTIVE AMOUNT OF A COMPOUND FOR STROKES | G.D. SEARLE & CO. | 2002-10-01 | — | — | US | claimed |
| US-20010018446-A1 | Substituted N-Aliphatic-N-Aromatictertiary-Heteroalkylamines useful for inhibiting cholesteryl ester transfer protein activity | G.D. SEARLE & CO. (US) | 2001-08-30 | — | — | US | claimed |
| US-11581567-B2 | Lithium ion battery and electrolyte thereof | CONTEMPORARY AMPEREX TECHNOLOGY CO., LIMITED (CN) | 2023-02-14 | — | — | US | disclosed |
| CN-113105425-B | Anti-inflammatory compound, preparation method and anti-inflammatory application thereof | 东北大学 | 2022-07-01 | — | — | CN | disclosed |
| CN-113105425-A | Anti-inflammatory compound, preparation method and anti-inflammatory application thereof | 东北大学 | 2021-07-13 | — | — | CN | disclosed |
| US-10971757-B2 | Lithium-ion battery and its electrolyte | CONTEMPORARY AMPEREX TECHNOLOGY CO., LIMITED (CN) | 2021-04-06 | — | — | US | disclosed |
| US-10826120-B2 | Lithium-ion battery and its electrolyte | CONTEMPORARY AMPEREX TECHNOLOGY CO., LIMITED (CN) | 2020-11-03 | — | — | US | disclosed |
| US-6451830-B1 | Use of substituted N,N-disubstituted non-fused heterocyclo amino compounds for inhibiting cholesteryl ester transfer protein activity | G.D. SEARLE & CO. | 2002-09-17 | — | — | US | disclosed |
| US-6448295-B1 | TREATING CARDIOVASCULAR DISEASE; ATHEROSCLEROSIS, DYSLIPIDEMA HYPERCHOLESTEROLAEMIA; DECREASING CONCENTRATIONS OF LOW DENSITY LIPOPROTEIN AND RAISING LEVEL OF HIGH DENSITY LIPOPROTEIN | G.D. SEARLE & CO. | 2002-09-10 | — | — | US | disclosed |
| US-20020058767-A1 | Method for producing an olefin type copolymer having a cyclic structure | MARUZEN PETROCHEMICAL CO., LTD. (JP) | 2002-05-16 | — | — | US | disclosed |
| EP-1205497-A2 | Method for producing an olefin type copolymer having a cyclic structure | MARUZEN PETROCHEMICAL CO., LTD. (JP) | 2002-05-15 | — | — | EP | disclosed |
| US-5219477-A | Containing organometallic salts and inorganic metal borates; fromo reactinmetal hydroxide with phenols or aromatic carboxylic acid | THE DOW CHEMICAL COMPANY (US) | 1993-06-15 | — | — | US | disclosed |
| US-5194652-A | High temperature lubricants, hydraulic fluids; jet aircraft, turbines, diesel engines | THE DOW CHEMICAL COMPANY (US) | 1993-03-16 | — | — | US | disclosed |