Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 9/20 | 0.43 |
| ▸ | PTGES2 | Q9H7Z7 | 6/20 | 0.41 |
| ▸ | CA12 | O43570 | 3/20 | 0.41 |
| ▸ | CA9 | Q16790 | 3/20 | 0.41 |
| ▸ | CA1 | P00915 | 2/20 | 0.41 |
| ▸ | CA4 | P22748 | 1/20 | 0.41 |
| ▸ | CA6 | P23280 | 1/20 | 0.41 |
| ▸ | CA5A | P35218 | 1/20 | 0.41 |
| ▸ | CA7 | P43166 | 1/20 | 0.41 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.41 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.41 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.40 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8023270 | 0.86 | PTGS2 (0.50) | CA2PTGES2CA12CA9CA1 | |
| SCHEMBL28288866 | 0.84 | HTR2A (0.46) | CA2PTGES2CA12CA9CA1 | |
| SCHEMBL27807468 | 0.82 | MPO (0.50) | CA2PTGES2CA12CA9CA1 | |
| SCHEMBL27727227 | 0.81 | CA2 (0.42) | CA2CA12CA9CA1CA4 | |
| SCHEMBL7433447 | 0.80 | CA2 (0.42) | CA2PTGES2CA12CA9CA1 | |
| SCHEMBL3277846 | 0.80 | CA2 (0.44) | CA2PTGES2CA12CA9CA1 | |
| SCHEMBL1806652 | 0.79 | CA2 (0.41) | CA2PTGES2CA12CA9CA1 | |
| SCHEMBL27663182 | 0.79 | CA2 (0.42) | CA2PTGES2CA12CA9CA1 | |
| Hydrochloric Acid SCHEMBL1019715 | 0.79 | CA2 (0.41) | CA2PTGES2CA12CA9CA1 | |
| Sulfuric Acid SCHEMBL28952579 | 0.78 | CA2 (0.40) | CA2CA12CA9CA1CA4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7700654-B2 | Isolation of N-butylbenzenesulfonamide, synthesis of benzenesulfonamide derivatives, and use of N-butylbenzenesulfonamide and benzenesulfonamide derivatives for treating benign prostatic hyperplasia and/or prostate carcinoma | LTS LOHMANN THERAPIE-SYSTEME AG (DE) | 2010-04-20 | — | — | US | disclosed |
| WO-2000066562-A1 | PYRAZOLES HAVING ANTIINFLAMMATORY ACTIVITY | DR. REDDY'S RESEARCH FOUNDATION (IN) | 2000-11-09 | — | — | WO | disclosed |