Dimethylamine

SCHEMBL3279441

CC(C)OC(=O)NCCC(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)F.CNC

nearest known ligand 0.36

Predicted protein targets (top 13)

	gene	UniProt	supporting neighbours	confidence
▸	SMN1; SMN2	Q16637	2/20	0.33

▸	ALOX15	P16050	1/20	0.33

▸	HTT	P42858	2/20	0.32

▸	LMNA	P02545	1/20	0.32

▸	MEN1	O00255	1/20	0.32

▸	CYP1A2	P05177	1/20	0.32

▸	MAPT	P10636	1/20	0.32

▸	CYP2C9	P11712	1/20	0.32

▸	TSHR	P16473	1/20	0.32

▸	MAPK1	P28482	1/20	0.32

▸	CYP2C19	P33261	1/20	0.32

▸	KMT2A	Q03164	1/20	0.32

▸	BRD4	O60885	2/20	0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL6979841	0.97	SMN1; SMN2 (0.34)	SMN1; SMN2ALOX15HTTLMNAMEN1
SCHEMBL12901677	0.74	GAA (0.37)	TSHR
SCHEMBL17192467	0.73	MEN1 (0.31)	MEN1MAPTKMT2ABRD4
SCHEMBL13617116	0.72	ALOX15 (0.40)	SMN1; SMN2ALOX15HTTLMNAMEN1
SCHEMBL12200835	0.72	GAA (0.38)	TSHR
SCHEMBL13827121	0.71	GBA1 (0.33)	SMN1; SMN2MEN1KMT2A
SCHEMBL12707860	0.69	ALOX15 (0.38)	SMN1; SMN2ALOX15HTTLMNAMEN1
SCHEMBL2998940	0.69	CA2 (0.31)	—
SCHEMBL12199962	0.69	CA2 (0.31)	—
SCHEMBL6029680	0.68	GBA1 (0.37)	—

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
US-7700794-B2	Fluorous tagging compounds and methods of increasing the fluorous nature of compounds	UNIVERSITY OF PITTSBURGH - OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION (US)	2010-04-20	—	—	US	disclosed