Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | BRD4 | O60885 | 3/20 | 0.32 |
| ▸ | KCNJ11 | Q14654 | 1/20 | 0.31 |
| ▸ | CA2 | P00918 | 1/20 | 0.30 |
| ▸ | GBA1 | P04062 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Dimethylamine SCHEMBL3279441 | 0.97 | SMN1; SMN2 (0.33) | SMN1; SMN2ALOX15HTTLMNAMEN1 | |
| SCHEMBL12901677 | 0.76 | GAA (0.37) | TSHRCA2GBA1 | |
| SCHEMBL17192467 | 0.76 | MEN1 (0.31) | MEN1MAPTKMT2ABRD4 | |
| SCHEMBL13617116 | 0.74 | ALOX15 (0.40) | SMN1; SMN2ALOX15HTTLMNAMEN1 | |
| SCHEMBL12200835 | 0.74 | GAA (0.38) | TSHRCA2 | |
| SCHEMBL13827121 | 0.74 | GBA1 (0.33) | SMN1; SMN2MEN1KMT2ACA2GBA1 | |
| SCHEMBL12707860 | 0.71 | ALOX15 (0.38) | SMN1; SMN2ALOX15HTTLMNAMEN1 | |
| SCHEMBL12199962 | 0.71 | CA2 (0.31) | CA2GBA1 | |
| SCHEMBL2998940 | 0.71 | CA2 (0.31) | CA2GBA1 | |
| SCHEMBL5386730 | 0.70 | GBA1 (0.37) | CA2GBA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1280765-A2 | FLUOROUS TAGGING COMPOUNDS AND THEIR USE | UNIVERSITY OF PITTSBURGH (US) | 2003-02-05 | — | — | EP | disclosed |
| WO-2001085675-A2 | FLUOROUS TAGGING COMPOUNDS AND THEIR USE | UNIVERSITY OF PITTSBURGH (US) | 2001-11-15 | — | — | WO | disclosed |