Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 4/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.57 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | TP53 | P04637 | 2/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | GLA | P06280 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 2/20 | 0.40 |
| ▸ | CXCR2 | P25025 | 1/20 | 0.40 |
| ▸ | CA12 | O43570 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | CA4 | P22748 | 1/20 | 0.39 |
| ▸ | CA7 | P43166 | 1/20 | 0.39 |
| ▸ | CA9 | Q16790 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL188296 | 0.85 | MEN1 (0.65) | MEN1KMT2ASMN1; SMN2KEAP1ALDH1A1 | |
| SCHEMBL12545912 | 0.78 | MEN1 (0.53) | MEN1KMT2ASMN1; SMN2KEAP1HPGD | |
| SCHEMBL8534092 | 0.78 | ALDH1A1 (0.69) | MEN1KMT2ASMN1; SMN2KEAP1ALDH1A1 | |
| SCHEMBL943874 | 0.78 | POLB (0.57) | MEN1KMT2ASMN1; SMN2KEAP1ALDH1A1 | |
| SCHEMBL30037151 | 0.77 | KMT2A (0.59) | MEN1KMT2ASMN1; SMN2KEAP1ALDH1A1 | |
| SCHEMBL3279730 | 0.77 | KMT2A (0.57) | MEN1KMT2ASMN1; SMN2KEAP1ALDH1A1 | |
| SCHEMBL1018643 | 0.77 | ALDH1A1 (0.64) | MEN1KMT2ASMN1; SMN2KEAP1ALDH1A1 | |
| SCHEMBL1446966 | 0.77 | MEN1 (0.57) | MEN1KMT2ASMN1; SMN2KEAP1ALDH1A1 | |
| SCHEMBL354228 | 0.77 | KMT2A (0.59) | MEN1KMT2ASMN1; SMN2KEAP1ALDH1A1 | |
| SCHEMBL14164778 | 0.77 | MEN1 (0.57) | MEN1KMT2ASMN1; SMN2KEAP1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10251396-B2 | Amide compound and use of same for noxious arthropod control | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2019-04-09 | — | — | US | disclosed |
| US-20170295789-A1 | AMIDE COMPOUND AND USE OF SAME FOR NOXIOUS ARTHROPOD CONTROL | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2017-10-19 | — | — | US | disclosed |
| EP-3178322-A1 | AMIDE COMPOUND AND USE OF SAME FOR NOXIOUS ARTHROPOD CONTROL | Sumitomo Chemical Company Limited (JP) | 2017-06-14 | — | — | EP | disclosed |
| EP-1702919-B1 | NOVEL 2-HETEROARYL-SUBSTITUTED BENZIMIDAZOLE DERIVATIVE | MSD KK (JP) | 2012-05-30 | — | — | EP | disclosed |
| US-7728025-B2 | 2-heteroaryl-substituted benzimidazole derivative | BANYU PHARMACEUTICAL CO., LTD. (JP) | 2010-06-01 | — | — | US | disclosed |
| US-20080070928-A1 | Novel 2-Heteroaryl-Substituted Benzimidazole Derivative | MSD K.K. (JP) | 2008-03-20 | — | — | US | disclosed |
| EP-1702919-A1 | NOVEL 2-HETEROARYL-SUBSTITUTED BENZIMIDAZOLE DERIVATIVE | BANYU PHARMACEUTICAL CO., LTD. (JP) | 2006-09-20 | — | — | EP | disclosed |
| EP-0299362-B1 | PROCESS FOR PREPARING PYRIDINE-2,3- DICARBOXYLIC ACID COMPOUNDS | Daiso Co., Ltd. (JP) | 1991-12-04 | — | — | EP | disclosed |
| US-4999426-A | Preparation of 4-azasaccharines | CIBA-GEIGY CORPORATION (US) | 1991-03-12 | — | — | US | disclosed |
| US-4948896-A | REACTING AN ENONE AND AN AMINODIESTER | DAISO CO., LTD. (JP) | 1990-08-14 | — | — | US | disclosed |
| US-4889933-A | HERBICIDES | CIBA-GEIGY CORPORATION (US) | 1989-12-26 | — | — | US | disclosed |
| EP-0308371-A1 | 4-Aza-saccharines, 4-aza-dihydro- or -tetrahydrosaccharines and process for their preparation | CIBA-GEIGY AG (CH) | 1989-03-22 | — | — | EP | disclosed |
| EP-0299362-A1 | Process for preparing pyridine-2,3- dicarboxylic acid compounds | Daiso Co., Ltd. (JP) | 1989-01-18 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170295789-A1 | AMIDE COMPOUND AND USE OF SAME FOR NOXIOUS ARTHROPOD CONTROL | OPRM1, TRPA1, L3MBTL3 | MEN1 4192/4885KMT2A 1451/4885SMN1; SMN2 1274/4885 |
| US-20080070928-A1 | Novel 2-Heteroaryl-Substituted Benzimidazole Derivative | GCK, GCKR, HK1 | MEN1 4085/4885KMT2A 1946/4885SMN1; SMN2 832/4885 |
| US-10251396-B2 | Amide compound and use of same for noxious arthropod control | OPRM1, TRPA1, L3MBTL3 | MEN1 4192/4885KMT2A 1451/4885SMN1; SMN2 1274/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.