Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.68 |
| ▸ | NPC1 | O15118 | 1/20 | 0.65 |
| ▸ | GAA | P10253 | 1/20 | 0.65 |
| ▸ | RAB9A | P51151 | 1/20 | 0.65 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.65 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.64 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.64 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.64 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.62 |
| ▸ | MAPT | P10636 | 2/20 | 0.62 |
| ▸ | HTT | P42858 | 1/20 | 0.62 |
| ▸ | CA12 | O43570 | 1/20 | 0.61 |
| ▸ | CA1 | P00915 | 1/20 | 0.61 |
| ▸ | CA2 | P00918 | 1/20 | 0.61 |
| ▸ | CA9 | Q16790 | 1/20 | 0.61 |
| ▸ | PLAAT3 | P53816 | 1/20 | 0.61 |
| ▸ | PLAAT5 | Q96KN8 | 1/20 | 0.61 |
| ▸ | PLAAT2 | Q9NWW9 | 1/20 | 0.61 |
| ▸ | PLAAT4 | Q9UL19 | 1/20 | 0.61 |
| ▸ | MEN1 | O00255 | 2/20 | 0.61 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7265002 | 0.84 | CA12 (0.73) | ALDH1A1GAAKMT2AMAPTCA12 | |
| SCHEMBL3281488 | 0.83 | MAPT (0.69) | ALDH1A1RAB9AKMT2AMAPTHTT | |
| SCHEMBL4027064 | 0.82 | SMN1; SMN2 (0.87) | ALDH1A1KMT2AMAPTHTTMEN1 | |
| SCHEMBL901614 | 0.82 | CA12 (0.73) | ALDH1A1GAAKMT2AMAPTCA12 | |
| SCHEMBL29356619 | 0.81 | ALDH1A1 (0.77) | ALDH1A1NPC1GAARAB9AKMT2A | |
| SCHEMBL6270935 | 0.81 | ALDH1A1 (0.77) | ALDH1A1NPC1GAARAB9AKMT2A | |
| SCHEMBL7115429 | 0.80 | GAA (0.70) | ALDH1A1NPC1GAARAB9AKMT2A | |
| SCHEMBL6280197 | 0.80 | CA12 (0.56) | ALDH1A1KMT2AMAPTHTTCA12 | |
| SCHEMBL6380843 | 0.80 | ALDH1A1 (0.70) | ALDH1A1TAAR1KMT2AMAPTHTT | |
| SCHEMBL25987693 | 0.80 | SLC7A5 (0.68) | ALDH1A1NPC1GAARAB9ATAAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7696374-B2 | Arylalklcarbamate derivatives, preparation method thereof and use of same in therapeutics | SANOFI-AVENTIS (FR) | 2010-04-13 | — | — | US | claimed |
| US-20060223805-A1 | Arylalklcarbamate derivatives, preparation method thereof and use of same in therapeutics | SANOFI-AVENTIS (FR) | 2006-10-05 | — | — | US | claimed |
| US-7696374-B2 | Arylalklcarbamate derivatives, preparation method thereof and use of same in therapeutics | SANOFI-AVENTIS (FR) | 2010-04-13 | — | — | US | disclosed |
| EP-1972616-A1 | Derivatives of arylalkylcarbamates, process for their preparation and therapeutic application thereof | Sanofi-Aventis (FR) | 2008-09-24 | — | — | EP | disclosed |
| US-20060223805-A1 | Arylalklcarbamate derivatives, preparation method thereof and use of same in therapeutics | SANOFI-AVENTIS (FR) | 2006-10-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060223805-A1 | Arylalklcarbamate derivatives, preparation method thereof and use of same in therapeutics | GBA1, NAT1, AADAC | ALDH1A1 32/4885NPC1 45/4885GAA 97/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.