Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 2/20 | 0.42 |
| ▸ | MAOB | P27338 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.41 |
| ▸ | MEN1 | O00255 | 4/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.41 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.40 |
| ▸ | SLC18A3 | Q16572 | 1/20 | 0.40 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1338448 | 0.76 | PLAU (0.46) | — | |
| SCHEMBL30444390 | 0.72 | SLC18A3 (0.47) | MAOAMAOBKMT2AMEN1MAPT | |
| SCHEMBL4271101 | 0.72 | SLC18A3 (0.47) | MAOAMAOBKMT2AMEN1MAPT | |
| SCHEMBL29447885 | 0.67 | PLAU (0.52) | MAOAMAOB | |
| SCHEMBL691836 | 0.67 | PLAU (0.52) | MAOAMAOB | |
| SCHEMBL13929740 | 0.67 | PLAU (0.52) | MAOAMAOB | |
| SCHEMBL56072 | 0.67 | MAOA (0.54) | MAOAMAOBKMT2AMEN1MAPT | |
| SCHEMBL29501453 | 0.67 | SLC18A3 (0.49) | MAOAMAOBKMT2AKEAP1SLC18A3 | |
| SCHEMBL2240961 | 0.65 | ALDH1A1 (0.34) | — | |
| SCHEMBL3834171 | 0.65 | MAOA (0.50) | MAOAMAOBKMT2AMEN1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7700794-B2 | Fluorous tagging compounds and methods of increasing the fluorous nature of compounds | UNIVERSITY OF PITTSBURGH - OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION (US) | 2010-04-20 | — | — | US | disclosed |
| US-20050096478-A1 | Fluorous tagging compounds and methods of increasing the fluorous nature of compounds | UNIVERSITY OF PITTSBURGH | 2005-05-05 | — | — | US | disclosed |
| US-6825043-B1 | FOR DRUG SCREENING/CATALYST DESIGN | UNIVERSITY OF PITTSBURGH | 2004-11-30 | — | — | US | disclosed |
| EP-1280765-A2 | FLUOROUS TAGGING COMPOUNDS AND THEIR USE | UNIVERSITY OF PITTSBURGH (US) | 2003-02-05 | — | — | EP | disclosed |
| WO-2001085675-A2 | FLUOROUS TAGGING COMPOUNDS AND THEIR USE | UNIVERSITY OF PITTSBURGH (US) | 2001-11-15 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050096478-A1 | Fluorous tagging compounds and methods of increasing the fluorous nature of compounds | AFF1, AFF2, AFF4 | MAOA 2205/4885MAOB 1734/4885KMT2A 992/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.