Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6129127 | 0.81 | F2 (0.32) | THRB | |
| SCHEMBL3283244 | 0.81 | THRB (0.31) | THRB | |
| SCHEMBL2508311 | 0.78 | ALDH1A1 (0.31) | — | |
| SCHEMBL5857962 | 0.78 | ALDH1A1 (0.31) | — | |
| SCHEMBL3285319 | 0.75 | MEN1 (0.33) | — | |
| SCHEMBL7643011 | 0.68 | LMNA (0.42) | THRB | |
| SCHEMBL7641162 | 0.68 | LMNA (0.42) | THRB | |
| SCHEMBL5858721 | 0.68 | ALDH1A1 (0.31) | — | |
| SCHEMBL3279169 | 0.68 | THRB (0.31) | THRB | |
| SCHEMBL2513861 | 0.68 | ALDH1A1 (0.48) | THRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7700794-B2 | Fluorous tagging compounds and methods of increasing the fluorous nature of compounds | UNIVERSITY OF PITTSBURGH - OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION (US) | 2010-04-20 | — | — | US | disclosed |
| US-20050096478-A1 | Fluorous tagging compounds and methods of increasing the fluorous nature of compounds | UNIVERSITY OF PITTSBURGH | 2005-05-05 | — | — | US | disclosed |
| US-6825043-B1 | FOR DRUG SCREENING/CATALYST DESIGN | UNIVERSITY OF PITTSBURGH | 2004-11-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050096478-A1 | Fluorous tagging compounds and methods of increasing the fluorous nature of compounds | AFF1, AFF2, AFF4 | THRB 2500/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.