Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.44 |
| ▸ | HTT | P42858 | 2/20 | 0.44 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.42 |
| ▸ | STAT1 | P42224 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.42 |
| ▸ | RELA | Q04206 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7664875 | 0.83 | LMNA (0.50) | LMNAHTTABCC4GAATSHR | |
| SCHEMBL27814178 | 0.81 | MKNK1 (0.50) | LMNAGAATSHRNPC1HPGD | |
| SCHEMBL29239614 | 0.80 | TSHR (0.42) | LMNAHTTABCC4GAATSHR | |
| SCHEMBL3999483 | 0.80 | TAAR1 (0.55) | NPC1HPGDKDM4ESMN1; SMN2ALDH1A1 | |
| SCHEMBL1395755 | 0.78 | LMNA (0.69) | LMNAHTTABCC4GAATSHR | |
| SCHEMBL25394857 | 0.77 | NPC1 (0.47) | GAATSHRNPC1HPGDRAB9A | |
| SCHEMBL28164518 | 0.77 | FAAH (0.38) | LMNAHTTABCC4GAATSHR | |
| SCHEMBL25395879 | 0.77 | NPC1 (0.47) | GAATSHRNPC1HPGDRAB9A | |
| SCHEMBL180350 | 0.77 | TSHR (0.42) | LMNAHTTABCC4GAATSHR | |
| SCHEMBL483513 | 0.77 | NPC1 (0.47) | GAATSHRNPC1HPGDRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1494694-B1 | Photo-active backbone cyclized somatostatin analogs for photodynamic therapy and imaging | DEVELOGEN ISRAEL LTD (IL) | 2013-05-08 | — | — | EP | claimed |
| US-7700717-B2 | Photo-active backbone cyclized somatostatin analogs for photodynamic therapy and imaging | DEVELOGEN ISRAEL LTD. (IL) | 2010-04-20 | — | — | US | claimed |
| US-20050090429-A1 | Photo-active backbone cyclized somatostatin analogs for photodynamic therapy and imaging | TEL HASHOMER - MEDICAL RESEARCH, INFRASTRUCTURE AND SERVICES LTD. (IL) | 2005-04-28 | — | — | US | claimed |
| EP-1494694-B1 | Photo-active backbone cyclized somatostatin analogs for photodynamic therapy and imaging | DEVELOGEN ISRAEL LTD (IL) | 2013-05-08 | — | — | EP | disclosed |
| US-7700717-B2 | Photo-active backbone cyclized somatostatin analogs for photodynamic therapy and imaging | DEVELOGEN ISRAEL LTD. (IL) | 2010-04-20 | — | — | US | disclosed |
| US-20050090429-A1 | Photo-active backbone cyclized somatostatin analogs for photodynamic therapy and imaging | TEL HASHOMER - MEDICAL RESEARCH, INFRASTRUCTURE AND SERVICES LTD. (IL) | 2005-04-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050090429-A1 | Photo-active backbone cyclized somatostatin analogs for photodynamic therapy and imaging | SSTR4, SSTR1, SSTR3 | LMNA 4153/4885HTT 1290/4885ABCC4 3641/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.