Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP1 | P09874 | 2/20 | 0.37 |
| ▸ | LCK | P06239 | 1/20 | 0.36 |
| ▸ | CHEK2 | O96017 | 4/20 | 0.34 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.34 |
| ▸ | GRM5 | P41594 | 2/20 | 0.34 |
| ▸ | APP | P05067 | 2/20 | 0.33 |
| ▸ | F10 | P00742 | 1/20 | 0.32 |
| ▸ | JAK2 | O60674 | 1/20 | 0.32 |
| ▸ | JAK1 | P23458 | 1/20 | 0.32 |
| ▸ | TYK2 | P29597 | 1/20 | 0.32 |
| ▸ | JAK3 | P52333 | 1/20 | 0.32 |
| ▸ | HPGDS | O60760 | 1/20 | 0.31 |
| ▸ | CSF1R | P07333 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3277024 | 0.80 | GRM5 (0.41) | PARP1GRM5JAK2TSHRKMT2A | |
| Hydrochloric Acid SCHEMBL14230990 | 0.79 | GRM5 (0.40) | PARP1GRM5JAK2TSHRKMT2A | |
| SCHEMBL13717134 | 0.65 | KDM4E (0.48) | GRM5KMT2A | |
| SCHEMBL2973768 | 0.63 | PARP15 (0.46) | PARP1LCKCYP11B2TSHRKMT2A | |
| SCHEMBL13717468 | 0.63 | ALDH1A1 (0.41) | TSHR | |
| SCHEMBL15464961 | 0.63 | CYP11B2 (0.60) | PARP1CYP11B2 | |
| SCHEMBL3085415 | 0.63 | CYP11B2 (0.49) | PARP1LCKCYP11B2JAK2 | |
| SCHEMBL2363489 | 0.61 | LCK (0.78) | PARP1LCKTSHRKMT2A | |
| SCHEMBL3277025 | 0.60 | APP (0.54) | GRM5APPKMT2A | |
| SCHEMBL29781365 | 0.60 | CES2 (0.67) | PARP1LCKTSHRKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8242307-B1 | Site-specific cleavage of nucleic acids by photoreactive conjugates | FLORIDA STATE UNIVERSITY RESEARCH FOUNDATION, INC. (US) | 2012-08-14 | — | — | US | disclosed |
| US-7695912-B1 | Site-specific cleavage of nucleic acids by photoreactive conjugates | FLORIDA STATE UNIVERSITY RESEARCH FOUNDATION, INC. (US) | 2010-04-13 | — | — | US | disclosed |