Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1B | P49286 | 1/20 | 0.49 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.42 |
| ▸ | NAMPT | P43490 | 1/20 | 0.42 |
| ▸ | ABL1 | P00519 | 1/20 | 0.42 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.41 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | CRHBP | P24387 | 1/20 | 0.41 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.41 |
| ▸ | NOX1 | Q9Y5S8 | 1/20 | 0.41 |
| ▸ | FLT1 | P17948 | 1/20 | 0.41 |
| ▸ | KDR | P35968 | 1/20 | 0.41 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.41 |
| ▸ | GBA1 | P04062 | 1/20 | 0.41 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL3270278 | 0.95 | MTNR1B (0.45) | MTNR1BMAPK14NAMPTABL1ALOX5 | |
| SCHEMBL3269527 | 0.91 | ALOX5 (0.50) | MAPK14ALOX5EPHX2NPC1RAB9A | |
| SCHEMBL3278196 | 0.91 | KMT2A (0.47) | NAMPTMAPTKDRROCK2MCHR1 | |
| SCHEMBL3275815 | 0.89 | GBA1 (0.46) | MAPK14ALOX5EPHX2NPC1RAB9A | |
| SCHEMBL3270368 | 0.88 | NPC1 (0.52) | NPC1RAB9AMAPTHPGDCYP2C19 | |
| SCHEMBL4457369 | 0.88 | MEN1 (0.48) | MTNR1BMAPTHPGDMCL1CYP2C19 | |
| SCHEMBL3270529 | 0.87 | MAPK1 (0.47) | MAPK14ALOX5EPHX2HPGDMCL1 | |
| SCHEMBL3273871 | 0.87 | NPC1 (0.50) | MAPK14NAMPTNPC1RAB9AHPGD | |
| SCHEMBL3270361 | 0.87 | MCL1 (0.40) | MTNR1BABL1NPC1RAB9AMAPT | |
| Trifluoroacetic Acid SCHEMBL3269765 | 0.86 | KMT2A (0.43) | EPHX2MAPTKDRROCK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2024335-B1 | NOVEL IMIDAZOLE DERIVATIVES, PREPARATION AND USER THEREOF AS MEDICINE | IPSEN PHARMA (FR) | 2010-06-23 | — | — | EP | disclosed |
| EP-2024335-A1 | NOVEL IMIDAZOLE DERIVATIVES, PREPARATION AND USER THEREOF AS MEDICINE | Societe de Conseils de Recherches et d'Applications Scientifique (FR) | 2009-02-18 | — | — | EP | disclosed |
| WO-2007125197-A1 | NOVEL IMIDAZOLE DERIVATIVES, PREPARATION AND USER THEREOF AS MEDICINE | SOCIETE DE CONSEILS DE RECHERCHES ET D'APPLICATIONS SCIENTIFIQUE (S.C.R.A.S.) (FR) | 2007-11-08 | — | — | WO | disclosed |