Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | TLR7 | Q9NYK1 | 2/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | PTGS2 | P35354 | 4/20 | 0.32 |
| ▸ | DHFR | P00374 | 1/20 | 0.32 |
| ▸ | CA2 | P00918 | 1/20 | 0.32 |
| ▸ | ESR1 | P03372 | 2/20 | 0.31 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.31 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.31 |
| ▸ | TACR2 | P21452 | 2/20 | 0.31 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.31 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.31 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7835691 | 0.83 | CDC25A (0.45) | TDP1MEN1KMT2AESR1ALDH1A1 | |
| SCHEMBL13361150 | 0.78 | KCNH2 (0.38) | TLR7KCNH2CYP3A4MEN1KMT2A | |
| SCHEMBL12881245 | 0.77 | KDM4E (0.31) | KDM4EALDH1A1 | |
| SCHEMBL25653978 | 0.76 | TLR7 (0.43) | TLR7KCNH2MEN1KMT2ADHFR | |
| SCHEMBL18599000 | 0.74 | IMPDH2 (0.36) | KCNH2MEN1KMT2AALDH1A1 | |
| SCHEMBL4782648 | 0.72 | HCAR2 (0.41) | TDP1L3MBTL1CYP3A4MEN1KMT2A | |
| SCHEMBL12866757 | 0.71 | — | — | |
| SCHEMBL1074604 | 0.70 | TDP1 (0.47) | TDP1L3MBTL1TLR7KCNH2CYP3A4 | |
| SCHEMBL532911 | 0.69 | MEN1 (0.36) | TDP1L3MBTL1TLR7KCNH2MEN1 | |
| SCHEMBL27818098 | 0.69 | TDP1 (0.45) | TDP1L3MBTL1TLR7KCNH2CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 67 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114014849-A | 4, 5-diaryl oxazole compound and application thereof | 福建医科大学 | 2022-02-08 | — | — | CN | claimed |
| CN-113651806-A | Preparation method of 4, 5-diaryl oxazole compound | 福建医科大学 | 2021-11-16 | — | — | CN | claimed |
| JP-5139030-A | — | — | None | — | — | JP | disclosed |
| EP-3102207-B1 | 2,4,5-TRI-SUBSTITUTED AZOLE-BASED CASEIN KINASE 1 INHIBITORS AS INDUCERS FOR CARDIOMYOGENESIS | AGENCY SCIENCE TECH & RES (SG) | 2022-05-11 | — | — | EP | disclosed |
| CN-114014849-A | 4, 5-diaryl oxazole compound and application thereof | 福建医科大学 | 2022-02-08 | — | — | CN | disclosed |
| CN-114014849-A | 4, 5-diaryl oxazole compound and application thereof | 福建医科大学 | 2022-02-08 | — | — | CN | disclosed |
| CN-114014849-A | 4, 5-diaryl oxazole compound and application thereof | 福建医科大学 | 2022-02-08 | — | — | CN | disclosed |
| CN-113651806-A | Preparation method of 4, 5-diaryl oxazole compound | 福建医科大学 | 2021-11-16 | — | — | CN | disclosed |
| CN-113651806-A | Preparation method of 4, 5-diaryl oxazole compound | 福建医科大学 | 2021-11-16 | — | — | CN | disclosed |
| CN-113651806-A | Preparation method of 4, 5-diaryl oxazole compound | 福建医科大学 | 2021-11-16 | — | — | CN | disclosed |
| US-20210188838-A1 | ANTI-BIOFILM COMPOUNDS | UNIVERSITY OF LOUISVILLE RESEARCH FOUNDATION, INC. (US) | 2021-06-24 | — | — | US | disclosed |
| US-5972965-A | USEFUL FOR INHIBITION OF PLATELET AGGREGATION, VASODILATION, ANTIHYPERTENSIVE ACTIVITY AND PROSTAGLANDIN AGONIST | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1999-10-26 | — | — | US | disclosed |
| WO-1999024397-A1 | BENZOCYCLOHEPTENE DERIVATIVES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1999-05-20 | — | — | WO | disclosed |
| WO-1999021843-A1 | 4, 5-DIARYLOXAZOLE COMPOUNDS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1999-05-06 | — | — | WO | disclosed |
| CN-1196726-A | 4,5-diaryl oxazole derivatives | FUJISAWA PHARMACEUTICAL CO (JP) | 1998-10-21 | — | — | CN | disclosed |
| EP-0736018-A1 | 4,5-DIARYLOXAZOLE DERIVATIVES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1996-10-09 | — | — | EP | disclosed |
| WO-1995017393-A1 | 4,5-DIARYLOXAZOLE DERIVATIVES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1995-06-29 | — | — | WO | disclosed |
| JP-H05139030-A | THERMAL RECORDING MATERIAL | MITSUI TOATSU CHEM INC | 1993-06-08 | — | — | JP | disclosed |
| US-4225666-A | Silver halide precipitation and methine dye spectral sensitization process and products thereof | EASTMAN KODAK COMPANY (US) | 1980-09-30 | — | — | US | disclosed |
| US-4183756-A | PRECIPITATION OF WILVER HALIDE PARTICLES IN PRESENCE OF METHINE DYE | EASTMAN KODAK COMPANY (US) | 1980-01-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210188838-A1 | ANTI-BIOFILM COMPOUNDS | FGB, SELP, SPPL2B | TDP1 2073/4885L3MBTL1 2716/4885TLR7 3260/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.