Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCAR2 | Q8TDS4 | 4/20 | 0.41 |
| ▸ | HCAR3 | P49019 | 1/20 | 0.41 |
| ▸ | RARB | P10826 | 6/20 | 0.40 |
| ▸ | PPARA | Q07869 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.38 |
| ▸ | RELA | Q04206 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 3/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11001539 | 0.82 | FBP1 (0.39) | ALDH1A1SMN1; SMN2MEN1KMT2AMAPT | |
| SCHEMBL1760311 | 0.82 | ADORA2A (0.36) | HCAR2ALDH1A1NFKB1NPC1RAB9A | |
| SCHEMBL8882444 | 0.80 | FBP1 (0.42) | PPARAALDH1A1MAPTKDM4ELMNA | |
| SCHEMBL15000448 | 0.79 | PLA2G4A (0.36) | HCAR2HCAR3RARBPPARAALDH1A1 | |
| SCHEMBL28119464 | 0.77 | THRA (0.34) | HCAR2HCAR3ALDH1A1NFKB1MEN1 | |
| SCHEMBL7835691 | 0.72 | CDC25A (0.45) | PPARAALDH1A1MEN1KMT2ATDP1 | |
| SCHEMBL3281297 | 0.72 | TDP1 (0.36) | ALDH1A1MEN1KMT2ATDP1KDM4E | |
| SCHEMBL4806017 | 0.71 | FBP1 (0.43) | HCAR2HCAR3RARBALDH1A1 | |
| SCHEMBL13361150 | 0.71 | KCNH2 (0.38) | ALDH1A1RAB9ASMN1; SMN2MEN1KMT2A | |
| SCHEMBL1082565 | 0.70 | HCAR2 (0.41) | HCAR2HCAR3RARBALDH1A1NFKB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008087611-A2 | PYRROLIDINE- AND PIPERIDINE- BIS-AMIDE DERIVATIVES | ACTELION PHARMACEUTICALS LTD (CH) | 2008-07-24 | — | — | WO | disclosed |
| US-4535089-A | Alkyloxazolylacetic acid derivative for the treatment of hyperlipidemia | TANABE SEIYAKU CO., LTD. (JP) | 1985-08-13 | — | — | US | disclosed |
| EP-0094612-A2 | Novel alkyloxazolylacetic acid derivative, processes for preparation and pharmaceutical compositions containing same | Tanabe Seiyaku Co., Ltd. (JP) | 1983-11-23 | — | — | EP | disclosed |