Ergosterol Peroxide

Ergosterol Peroxide

SCHEMBL3281353

CC(C)[C@@H](C)/C=C/[C@@H](C)[C@H]1CC[C@@H]2[C@]1(C)CC[C@H]1[C@]23C=C[C@]2(C[C@@H](O)CC[C@]12C)OO3

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ PLA2G1B P04054 2/20 0.46
▸ ALDH1A1 P00352 2/20 0.41
▸ ALOX15 P16050 2/20 0.41
▸ MAPT P10636 1/20 0.41
▸ MEN1 O00255 1/20 0.36
▸ NR1I2 O75469 1/20 0.36
▸ PGR P06401 1/20 0.36
▸ KMT2A Q03164 1/20 0.36
▸ VDR P11473 1/20 0.36
▸ LMNA P02545 2/20 0.35
▸ CYP3A4 P08684 2/20 0.35
▸ AR P10275 1/20 0.35
▸ TSHR P16473 1/20 0.35
▸ CYP2C9 P11712 1/20 0.35
▸ CYP2C19 P33261 1/20 0.35
▸ USP2 O75604 1/20 0.35
▸ ABCB11 O95342 1/20 0.35
▸ ESR1 P03372 1/20 0.35
▸ HSPD1 P10809 1/20 0.35
▸ PTGS1 P23219 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Ergosterol Peroxide SCHEMBL17368944 1.00 PLA2G1B (0.46) PLA2G1BALDH1A1ALOX15MAPTMEN1
Ergosterol Peroxide SCHEMBL14067806 1.00 PLA2G1B (0.46) PLA2G1BALDH1A1ALOX15MAPTMEN1
Ergosterol Peroxide SCHEMBL4537649 1.00 PLA2G1B (0.46) PLA2G1BALDH1A1ALOX15MAPTMEN1
Ergosterol Peroxide SCHEMBL3276091 1.00 PLA2G1B (0.46) PLA2G1BALDH1A1ALOX15MAPTMEN1
Ergosterol Peroxide SCHEMBL19715992 1.00 PLA2G1B (0.46) PLA2G1BALDH1A1ALOX15MAPTMEN1
SCHEMBL30249089 0.86 ALDH1A1 (0.35) PLA2G1BALDH1A1ALOX15MAPTMEN1
SCHEMBL16152196 0.79 PLA2G1B (0.55) PLA2G1BALDH1A1ALOX15MAPTMEN1
SCHEMBL8408231 0.79 PLA2G1B (0.55) PLA2G1BALDH1A1ALOX15MAPTMEN1
SCHEMBL30653161 0.79 PLA2G1B (0.55) PLA2G1BALDH1A1ALOX15MAPTMEN1
SCHEMBL4535338 0.69 ALDH1A1 (0.43) PLA2G1BALDH1A1ALOX15MAPTMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 51 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118108785-A 5 Alpha, 8 alpha-peroxy ergosterol-3-thiazolidinedione derivative, and preparation method and application thereof 齐齐哈尔医学院 2024-05-31 — — CN claimed
CN-112342194-B Application of peroxyergosterol in vitro culture of NK (natural killer) cells to improvement of lethality of NK cells 柏玉兰 2022-08-19 — — CN claimed
CN-114588167-A Application of ergosterol peroxide in preparation of medicine for inhibiting porcine delta coronavirus 中国农业大学 2022-06-07 — — CN claimed
CN-106692165-A Combined medicine for up-regulating PTEN gene expression to inhibit lung cancer cell growth 成都育芽科技有限公司 2017-05-24 — — CN claimed
CN-103740598-B One strain produce oil endogenetic fungus Salicorn5 and application thereof NANJING AGRICULTURAL UNIVERSITY (CN) 2016-04-06 — — CN claimed
CN-103740598-A Oil production endophytic fungi Salicorn5 and application thereof UNIV NANJING AGRICULTURAL 2014-04-23 — — CN claimed
CN-120504715-A 5 Alpha, 8 alpha-ergosterol peroxide-3-quaternary ammonium salt derivative and preparation method and application thereof 齐齐哈尔医学院 2025-08-19 — — CN disclosed
US-20250241930-A1 BIOLOGICALLY ACTIVE GANODERMA LUCIDUM COMPOUNDS AND SYNTHESIS OF ANTICANCER DERIVATIVES; ERGOSTEROL PEROXIDE PROBES FOR CELLULAR LOCALIZATION UNIV CENTRAL DEL CARIBE (US) 2025-07-31 — — US disclosed
US-12263177-B2 Biologically active ganoderma lucidum compounds and synthesis of anticancer derivatives; ergosterol peroxide probes for cellular localization UNIVERSIDAD CENTRAL DEL CARIBE (US) 2025-04-01 — — US disclosed
CN-119490555-A Method for extracting ergosterol product rich in peroxide from ganoderma lucidum 南京中科药业有限公司 2025-02-21 — — CN disclosed
CN-118108785-A 5 Alpha, 8 alpha-peroxy ergosterol-3-thiazolidinedione derivative, and preparation method and application thereof 齐齐哈尔医学院 2024-05-31 — — CN disclosed
CN-110891577-B Hair papilla cell growth promoter, FGF-7 production promoter, VEGF production promoter, IGF-1 production promoter, HGF production promoter, and hair growth promoter 株式会社姿美森 2023-11-28 — — CN disclosed
CN-115785189-B 5 alpha, 8 alpha-peroxosterol-17-phenylthiazole derivative and synthetic method and application thereof 齐齐哈尔医学院 2023-08-25 — — CN disclosed
CN-103740598-B One strain produce oil endogenetic fungus Salicorn5 and application thereof NANJING AGRICULTURAL UNIVERSITY (CN) 2016-04-06 — — CN disclosed
CN-104083382-A Synergistic effect and application of ergosterol peroxide and paclitaxel in aspect of killing Hela cancer cells UNIV INNER MONGOLIA 2014-10-08 — — CN disclosed
CN-103740598-A Oil production endophytic fungi Salicorn5 and application thereof UNIV NANJING AGRICULTURAL 2014-04-23 — — CN disclosed
US-20140080794-A1 Methods and Compositions for the Treatment of Estrogen-Dependent Hyperproliferative Uterine Disorders VIVUS INC (US) 2014-03-20 — — US disclosed
US-20100087402-A1 Methods and compositions for the treatment of estrogen-dependent hyperproliferative uterine disorders VIVUS, INC. (US) 2010-04-08 — — US disclosed
CN-100526330-C Fasciation naematoloma ligarine extraction, preparing method thereof and use in preparing pharmaceutical for treating tumour BAO HAIYING TULI KUER LI YU (CN) 2009-08-12 — — CN disclosed
CN-101012268-A Fasciation naematoloma ligarine extraction, preparing method thereof and use in preparing pharmaceutical for treating tumour BAO HAIYING (CN) 2007-08-08 — — CN disclosed
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