Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLA2G1B | P04054 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.36 |
| ▸ | PGR | P06401 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | VDR | P11473 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.35 |
| ▸ | AR | P10275 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | USP2 | O75604 | 1/20 | 0.35 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.35 |
| ▸ | ESR1 | P03372 | 1/20 | 0.35 |
| ▸ | HSPD1 | P10809 | 1/20 | 0.35 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Ergosterol Peroxide SCHEMBL14067806 | 1.00 | PLA2G1B (0.46) | PLA2G1BALDH1A1ALOX15MAPTMEN1 | |
| Ergosterol Peroxide SCHEMBL4537649 | 1.00 | PLA2G1B (0.46) | PLA2G1BALDH1A1ALOX15MAPTMEN1 | |
| Ergosterol Peroxide SCHEMBL3281353 | 1.00 | PLA2G1B (0.46) | PLA2G1BALDH1A1ALOX15MAPTMEN1 | |
| Ergosterol Peroxide SCHEMBL3276091 | 1.00 | PLA2G1B (0.46) | PLA2G1BALDH1A1ALOX15MAPTMEN1 | |
| Ergosterol Peroxide SCHEMBL19715992 | 1.00 | PLA2G1B (0.46) | PLA2G1BALDH1A1ALOX15MAPTMEN1 | |
| SCHEMBL30249089 | 0.86 | ALDH1A1 (0.35) | PLA2G1BALDH1A1ALOX15MAPTMEN1 | |
| SCHEMBL16152196 | 0.79 | PLA2G1B (0.55) | PLA2G1BALDH1A1ALOX15MAPTMEN1 | |
| SCHEMBL8408231 | 0.79 | PLA2G1B (0.55) | PLA2G1BALDH1A1ALOX15MAPTMEN1 | |
| SCHEMBL30653161 | 0.79 | PLA2G1B (0.55) | PLA2G1BALDH1A1ALOX15MAPTMEN1 | |
| SCHEMBL4535338 | 0.69 | ALDH1A1 (0.43) | PLA2G1BALDH1A1ALOX15MAPTMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20150374718-A1 | Zhankuic Acid A and Analogs thereof and Their Use as an Anti-Inflammatory Agent | NATIONAL CHENG KUNG UNIVERSITY (TW) | 2015-12-31 | — | — | US | disclosed |
| US-20150374718-A1 | Zhankuic Acid A and Analogs thereof and Their Use as an Anti-Inflammatory Agent | NATIONAL CHENG KUNG UNIVERSITY (TW) | 2015-12-31 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150374718-A1 | Zhankuic Acid A and Analogs thereof and Their Use as an Anti-Inflammatory Agent | CD14, LY96, TLR4 | PLA2G1B 1563/4885ALDH1A1 4498/4885ALOX15 2295/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.