Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.63 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.54 |
| ▸ | CA2 | P00918 | 4/20 | 0.49 |
| ▸ | CA1 | P00915 | 3/20 | 0.49 |
| ▸ | FPR2 | P25090 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | ATM | Q13315 | 1/20 | 0.47 |
| ▸ | ENPEP | Q07075 | 2/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | MME | P08473 | 1/20 | 0.43 |
| ▸ | ACE | P12821 | 1/20 | 0.43 |
| ▸ | CPA1 | P15085 | 1/20 | 0.43 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6534673 | 1.00 | ALDH1A1 (0.63) | ALDH1A1L3MBTL1CA2CA1FPR2 | |
| SCHEMBL1237677 | 1.00 | ALDH1A1 (0.63) | ALDH1A1L3MBTL1CA2CA1FPR2 | |
| SCHEMBL1234865 | 1.00 | ALDH1A1 (0.63) | ALDH1A1L3MBTL1CA2CA1FPR2 | |
| SCHEMBL1234867 | 1.00 | ALDH1A1 (0.63) | ALDH1A1L3MBTL1CA2CA1FPR2 | |
| SCHEMBL3281651 | 1.00 | ALDH1A1 (0.63) | ALDH1A1L3MBTL1CA2CA1FPR2 | |
| SCHEMBL6534356 | 1.00 | ALDH1A1 (0.63) | ALDH1A1L3MBTL1CA2CA1FPR2 | |
| SCHEMBL29866751 | 1.00 | ALDH1A1 (0.63) | ALDH1A1L3MBTL1CA2CA1FPR2 | |
| SCHEMBL9688830 | 0.84 | ALDH1A1 (0.59) | ALDH1A1L3MBTL1CA2CA1FPR2 | |
| SCHEMBL9688834 | 0.84 | ALDH1A1 (0.59) | ALDH1A1L3MBTL1CA2CA1FPR2 | |
| SCHEMBL18771897 | 0.83 | L3MBTL1 (0.47) | ALDH1A1L3MBTL1CA2CA1FPR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7709235-B2 | 5-Substituted hydantoin racemase, DNA encoding the same, recombinant DNA, transformed cell, and process for production of optically active N-carbamylamino acid or optically active amino acid | KANEKA CORPORATION (JP) | 2010-05-04 | — | — | US | claimed |
| US-20080261268-A1 | 5-Substituted Hydantoin Racemase, Dna Encoding the Same, Recombinant Dna, Transformed Cell, and Process for Production of Optically Active N-Carbamylamino Acid or Optically Active Amino Acid | KANEKA CORPORATION (JP) | 2008-10-23 | — | — | US | claimed |
| EP-1852510-A1 | 5-SUBSTITUTED HYDANTOIN RACEMASE, DNA ENCODING THE SAME, RECOMBINANT DNA, TRANSFORMED CELL, AND PROCESS FOR PRODUCTION OF OPTICALLY ACTIVE N-CARBAMYLAMINO ACID OR OPTICALLY ACTIVE AMINO ACID | Kaneka Corporation (JP) | 2007-11-07 | — | — | EP | claimed |
| US-6830904-B2 | Producing single diastereomers of isoleucine in high stereochemical purity by converting (R)-2-methylbutyraldehyde to a diastereomeric mixture of D-isoleucine hydantoin and L-allo-isoleucine hydantoin (5S-((R)-1-methylpropyl)hydantoin) | BIOCATALYTICS, INC. | 2004-12-14 | — | — | US | claimed |
| US-20040048342-A1 | Methods for producing diastereomers of isoleucine | CODEXIS, INC. | 2004-03-11 | — | — | US | claimed |
| EP-1209234-A1 | STEREOSTRUCTURE OF DECARBAMYLASE AND METHOD OF USING THE SAME | Kaneka Corporation (JP) | 2002-05-29 | — | — | EP | claimed |
| US-7709235-B2 | 5-Substituted hydantoin racemase, DNA encoding the same, recombinant DNA, transformed cell, and process for production of optically active N-carbamylamino acid or optically active amino acid | KANEKA CORPORATION (JP) | 2010-05-04 | — | — | US | disclosed |
| US-20080261268-A1 | 5-Substituted Hydantoin Racemase, Dna Encoding the Same, Recombinant Dna, Transformed Cell, and Process for Production of Optically Active N-Carbamylamino Acid or Optically Active Amino Acid | KANEKA CORPORATION (JP) | 2008-10-23 | — | — | US | disclosed |
| EP-1616945-B1 | Process for producing D-N-carbamoyl-alpha-amino acids | KANEGAFUCHI CHEMICAL IND (JP) | 2007-11-21 | — | — | EP | disclosed |
| EP-1852510-A1 | 5-SUBSTITUTED HYDANTOIN RACEMASE, DNA ENCODING THE SAME, RECOMBINANT DNA, TRANSFORMED CELL, AND PROCESS FOR PRODUCTION OF OPTICALLY ACTIVE N-CARBAMYLAMINO ACID OR OPTICALLY ACTIVE AMINO ACID | Kaneka Corporation (JP) | 2007-11-07 | — | — | EP | disclosed |
| EP-0801131-B1 | PROCESS FOR PRODUCING D-N-CARBAMOYL-ALPHA-AMINO ACID | KANEGAFUCHI CHEMICAL IND (JP) | 2007-02-21 | — | — | EP | disclosed |
| EP-1616945-A1 | Process for producing D-N-carbamoyl-alpha-amino acids | KANEGAFUCHI KAGAKU KOGYO KABUSHIKI KAISHA (JP) | 2006-01-18 | — | — | EP | disclosed |
| EP-1616946-A1 | Process for producing D-N-carbamoyl-alpha-amino acids | KANEGAFUCHI KAGAKU KOGYO KABUSHIKI KAISHA (JP) | 2006-01-18 | — | — | EP | disclosed |
| US-6830904-B2 | Producing single diastereomers of isoleucine in high stereochemical purity by converting (R)-2-methylbutyraldehyde to a diastereomeric mixture of D-isoleucine hydantoin and L-allo-isoleucine hydantoin (5S-((R)-1-methylpropyl)hydantoin) | BIOCATALYTICS, INC. | 2004-12-14 | — | — | US | disclosed |
| US-6830904-B2 | Producing single diastereomers of isoleucine in high stereochemical purity by converting (R)-2-methylbutyraldehyde to a diastereomeric mixture of D-isoleucine hydantoin and L-allo-isoleucine hydantoin (5S-((R)-1-methylpropyl)hydantoin) | BIOCATALYTICS, INC. | 2004-12-14 | — | — | US | disclosed |
| US-20040048342-A1 | Methods for producing diastereomers of isoleucine | CODEXIS, INC. | 2004-03-11 | — | — | US | disclosed |
| US-20040048342-A1 | Methods for producing diastereomers of isoleucine | CODEXIS, INC. | 2004-03-11 | — | — | US | disclosed |
| EP-1209234-A1 | STEREOSTRUCTURE OF DECARBAMYLASE AND METHOD OF USING THE SAME | Kaneka Corporation (JP) | 2002-05-29 | — | — | EP | disclosed |
| EP-0801131-A1 | PROCESS FOR PRODUCING D-N-CARBAMOYL-$g(a)-AMINO ACID | Kanegafuchi Chemical Industry Co., Ltd. (JP) | 1997-10-15 | — | — | EP | disclosed |