Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.63 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.54 |
| ▸ | CA2 | P00918 | 4/20 | 0.49 |
| ▸ | CA1 | P00915 | 3/20 | 0.49 |
| ▸ | FPR2 | P25090 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | ATM | Q13315 | 1/20 | 0.47 |
| ▸ | ENPEP | Q07075 | 2/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | MME | P08473 | 1/20 | 0.43 |
| ▸ | ACE | P12821 | 1/20 | 0.43 |
| ▸ | CPA1 | P15085 | 1/20 | 0.43 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6534673 | 1.00 | ALDH1A1 (0.63) | ALDH1A1L3MBTL1CA2CA1FPR2 | |
| SCHEMBL1237677 | 1.00 | ALDH1A1 (0.63) | ALDH1A1L3MBTL1CA2CA1FPR2 | |
| SCHEMBL1234865 | 1.00 | ALDH1A1 (0.63) | ALDH1A1L3MBTL1CA2CA1FPR2 | |
| SCHEMBL1234867 | 1.00 | ALDH1A1 (0.63) | ALDH1A1L3MBTL1CA2CA1FPR2 | |
| SCHEMBL3281651 | 1.00 | ALDH1A1 (0.63) | ALDH1A1L3MBTL1CA2CA1FPR2 | |
| SCHEMBL3281647 | 1.00 | ALDH1A1 (0.63) | ALDH1A1L3MBTL1CA2CA1FPR2 | |
| SCHEMBL29866751 | 1.00 | ALDH1A1 (0.63) | ALDH1A1L3MBTL1CA2CA1FPR2 | |
| SCHEMBL9688830 | 0.84 | ALDH1A1 (0.59) | ALDH1A1L3MBTL1CA2CA1FPR2 | |
| SCHEMBL9688834 | 0.84 | ALDH1A1 (0.59) | ALDH1A1L3MBTL1CA2CA1FPR2 | |
| SCHEMBL18771897 | 0.83 | L3MBTL1 (0.47) | ALDH1A1L3MBTL1CA2CA1FPR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6830904-B2 | Producing single diastereomers of isoleucine in high stereochemical purity by converting (R)-2-methylbutyraldehyde to a diastereomeric mixture of D-isoleucine hydantoin and L-allo-isoleucine hydantoin (5S-((R)-1-methylpropyl)hydantoin) | BIOCATALYTICS, INC. | 2004-12-14 | — | — | US | claimed |
| US-6822116-B2 | CONVERTING L-ISOLEUCINE TO CORRESPONDING HYDANTOIN; CONTACTING HYDANTOIN WITH D-HYDANTOINASE TO STEREOSELECTIVELY HYDROLYZE ANY D-ALLO-ISOLEUCINE HYDANTOIN IN MIXTURE TO CORRESPONDING N-CARBAMOYL-D-ALLO-ISOLEUCINE AND DECARBAMOYLATING | BIOCATALYTICS, INC. | 2004-11-23 | — | — | US | claimed |
| US-20040048342-A1 | Methods for producing diastereomers of isoleucine | CODEXIS, INC. | 2004-03-11 | — | — | US | claimed |
| US-20030219879-A1 | Method for producing D-allo -isoleucine | CODEXIS, INC. | 2003-11-27 | — | — | US | claimed |
| US-6830904-B2 | Producing single diastereomers of isoleucine in high stereochemical purity by converting (R)-2-methylbutyraldehyde to a diastereomeric mixture of D-isoleucine hydantoin and L-allo-isoleucine hydantoin (5S-((R)-1-methylpropyl)hydantoin) | BIOCATALYTICS, INC. | 2004-12-14 | — | — | US | disclosed |
| US-6822116-B2 | CONVERTING L-ISOLEUCINE TO CORRESPONDING HYDANTOIN; CONTACTING HYDANTOIN WITH D-HYDANTOINASE TO STEREOSELECTIVELY HYDROLYZE ANY D-ALLO-ISOLEUCINE HYDANTOIN IN MIXTURE TO CORRESPONDING N-CARBAMOYL-D-ALLO-ISOLEUCINE AND DECARBAMOYLATING | BIOCATALYTICS, INC. | 2004-11-23 | — | — | US | disclosed |
| US-6822116-B2 | CONVERTING L-ISOLEUCINE TO CORRESPONDING HYDANTOIN; CONTACTING HYDANTOIN WITH D-HYDANTOINASE TO STEREOSELECTIVELY HYDROLYZE ANY D-ALLO-ISOLEUCINE HYDANTOIN IN MIXTURE TO CORRESPONDING N-CARBAMOYL-D-ALLO-ISOLEUCINE AND DECARBAMOYLATING | BIOCATALYTICS, INC. | 2004-11-23 | — | — | US | disclosed |
| US-20040048342-A1 | Methods for producing diastereomers of isoleucine | CODEXIS, INC. | 2004-03-11 | — | — | US | disclosed |
| US-20030219879-A1 | Method for producing D-allo -isoleucine | CODEXIS, INC. | 2003-11-27 | — | — | US | disclosed |
| US-20030219879-A1 | Method for producing D-allo -isoleucine | CODEXIS, INC. | 2003-11-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030219879-A1 | Method for producing D-allo -isoleucine | DAO, DNPEP, AADAT | ALDH1A1 869/4885L3MBTL1 1344/4885CA2 1777/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.