Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAAH | O00519 | 1/20 | 0.58 |
| ▸ | HTT | P42858 | 2/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.56 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.56 |
| ▸ | NPC1 | O15118 | 2/20 | 0.53 |
| ▸ | RAB9A | P51151 | 2/20 | 0.53 |
| ▸ | EPHX1 | P07099 | 2/20 | 0.53 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.53 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.53 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.53 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.53 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.52 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.52 |
| ▸ | APEX1 | P27695 | 1/20 | 0.51 |
| ▸ | GID4 | Q8IVV7 | 1/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17346751 | 0.89 | ALDH1A1 (0.63) | FAAHHTTALDH1A1TAAR1NPC1 | |
| SCHEMBL5108159 | 0.84 | NPC1 (0.69) | HTTALDH1A1TAAR1NPC1RAB9A | |
| SCHEMBL241141 | 0.84 | ALDH1A1 (0.58) | FAAHHTTALDH1A1NPC1RAB9A | |
| SCHEMBL1680576 | 0.84 | ALDH1A1 (0.58) | HTTALDH1A1NPC1RAB9AEPHX1 | |
| SCHEMBL3274554 | 0.83 | NPC1 (0.65) | FAAHHTTALDH1A1TAAR1NPC1 | |
| SCHEMBL1196240 | 0.83 | MGLL (0.53) | FAAHTAAR1CYP2C9CYP2C19L3MBTL1 | |
| SCHEMBL23447430 | 0.82 | NPC1 (0.57) | HTTALDH1A1NPC1RAB9AEPHX1 | |
| SCHEMBL28397858 | 0.82 | ALDH1A1 (0.56) | FAAHHTTALDH1A1NPC1RAB9A | |
| SCHEMBL3282688 | 0.82 | TSHR (0.68) | FAAHHTTALDH1A1TAAR1NPC1 | |
| SCHEMBL22093747 | 0.82 | ALDH1A1 (0.56) | FAAHHTTALDH1A1TAAR1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7696374-B2 | Arylalklcarbamate derivatives, preparation method thereof and use of same in therapeutics | SANOFI-AVENTIS (FR) | 2010-04-13 | — | — | US | claimed |
| US-20060223805-A1 | Arylalklcarbamate derivatives, preparation method thereof and use of same in therapeutics | SANOFI-AVENTIS (FR) | 2006-10-05 | — | — | US | claimed |
| CN-107417578-B | N- (3, 5-dimethyl adamantane-1-yl) -N' -substituted phenylurea compound and preparation method and application thereof | 沈阳海诺威医药科技有限公司 | 2020-02-07 | — | — | CN | disclosed |
| CN-107417578-A | N (base of 3,5 dimethyladamantane 1) N ' substituted phenylurea compounds and its production and use | 沈阳海诺威医药科技有限公司 | 2017-12-01 | — | — | CN | disclosed |
| US-7696374-B2 | Arylalklcarbamate derivatives, preparation method thereof and use of same in therapeutics | SANOFI-AVENTIS (FR) | 2010-04-13 | — | — | US | disclosed |
| EP-1972616-A1 | Derivatives of arylalkylcarbamates, process for their preparation and therapeutic application thereof | Sanofi-Aventis (FR) | 2008-09-24 | — | — | EP | disclosed |
| US-20060223805-A1 | Arylalklcarbamate derivatives, preparation method thereof and use of same in therapeutics | SANOFI-AVENTIS (FR) | 2006-10-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060223805-A1 | Arylalklcarbamate derivatives, preparation method thereof and use of same in therapeutics | GBA1, NAT1, AADAC | FAAH 347/4885HTT 1883/4885ALDH1A1 32/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.