Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.63 |
| ▸ | HTT | P42858 | 1/20 | 0.63 |
| ▸ | NPC1 | O15118 | 2/20 | 0.60 |
| ▸ | RAB9A | P51151 | 2/20 | 0.60 |
| ▸ | EPHX1 | P07099 | 2/20 | 0.59 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.56 |
| ▸ | MGLL | Q99685 | 1/20 | 0.52 |
| ▸ | FAAH | O00519 | 1/20 | 0.52 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 1/20 | 0.51 |
| ▸ | PKM | P14618 | 1/20 | 0.51 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.51 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.51 |
| ▸ | GAA | P10253 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5108159 | 0.91 | NPC1 (0.69) | ALDH1A1HTTNPC1RAB9AEPHX1 | |
| SCHEMBL17863575 | 0.91 | MMP13 (0.58) | ALDH1A1HTTNPC1RAB9AEPHX1 | |
| SCHEMBL241141 | 0.91 | ALDH1A1 (0.58) | ALDH1A1HTTNPC1RAB9AEPHX1 | |
| SCHEMBL1680576 | 0.91 | ALDH1A1 (0.58) | ALDH1A1HTTNPC1RAB9AEPHX1 | |
| SCHEMBL23447430 | 0.89 | NPC1 (0.57) | ALDH1A1HTTNPC1RAB9AEPHX1 | |
| SCHEMBL3281978 | 0.89 | FAAH (0.58) | ALDH1A1HTTNPC1RAB9AEPHX1 | |
| SCHEMBL28397858 | 0.89 | ALDH1A1 (0.56) | ALDH1A1HTTNPC1RAB9AEPHX1 | |
| SCHEMBL17552096 | 0.87 | NPC1 (0.69) | ALDH1A1HTTNPC1RAB9AEPHX1 | |
| SCHEMBL24713417 | 0.85 | MAPK14 (0.66) | ALDH1A1HTTFAAHLMNAGAA | |
| SCHEMBL9263805 | 0.85 | NPC1 (0.67) | ALDH1A1HTTNPC1RAB9AEPHX1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11352319-B2 | Method for producing carbamate and method for producing isocyanate | ASAHI KASEI KABUSHIKI KAISHA (JP) | 2022-06-07 | — | — | US | disclosed |
| US-20210179548-A1 | METHOD FOR PRODUCING CARBAMATE AND METHOD FOR PRODUCING ISOCYANATE | ASAHI KASEI KABUSHIKI KAISHA (JP) | 2021-06-17 | — | — | US | disclosed |
| US-10968168-B2 | Isocyanate production method | ASAHI KASEI KABUSHIKI KAISHA (JP) | 2021-04-06 | — | — | US | disclosed |
| US-20200115327-A1 | ISOCYANATE PRODUCTION METHOD | ASAHI KASEI KABUSHIKI KAISHA (JP) | 2020-04-16 | — | — | US | disclosed |
| US-10338290-B2 | Cellulose ester film, polarizing plate, and liquid crystal display device | FUJIFILM CORPORATION (JP) | 2019-07-02 | — | — | US | disclosed |
| US-10040754-B2 | Cellulose acylate film, novel compound, polarizing plate and liquid crystal display device | FUJIFILM CORPORATION (JP) | 2018-08-07 | — | — | US | disclosed |
| US-20160370522-A1 | CELLULOSE ESTER FILM, POLARIZING PLATE, AND LIQUID CRYSTAL DISPLAY DEVICE | FUJIFILM CORPORATION (JP) | 2016-12-22 | — | — | US | disclosed |
| US-20160060405-A1 | POLYMER FILM, POLARIZING PLATE AND LIQUID CRYSTAL DISPLAY DEVICE | FUJIFILM CORPORATION (JP) | 2016-03-03 | — | — | US | disclosed |
| US-20150361036-A1 | CELLULOSE ACYLATE FILM, NOVEL COMPOUND, POLARIZING PLATE AND LIQUID CRYSTAL DISPLAY DEVICE | FUJIFILM CORPORATION (JP) | 2015-12-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11352319-B2 | Method for producing carbamate and method for producing isocyanate | CPS1, CA7, CA4 | ALDH1A1 781/4885HTT 2147/4885NPC1 2143/4885 |
| US-20200115327-A1 | ISOCYANATE PRODUCTION METHOD | IDH3A, ALKBH3, CPS1 | ALDH1A1 1502/4885HTT 2432/4885NPC1 2887/4885 |
| US-20210179548-A1 | METHOD FOR PRODUCING CARBAMATE AND METHOD FOR PRODUCING ISOCYANATE | CPS1, CA7, CA4 | ALDH1A1 781/4885HTT 2147/4885NPC1 2143/4885 |
| US-10968168-B2 | Isocyanate production method | IDH3A, ALKBH3, CPS1 | ALDH1A1 1502/4885HTT 2432/4885NPC1 2887/4885 |
| US-10040754-B2 | Cellulose acylate film, novel compound, polarizing plate and liquid crystal display device | NR1D1, NR1H2, NR1D2 | ALDH1A1 3058/4885HTT 4251/4885NPC1 456/4885 |
| US-20150361036-A1 | CELLULOSE ACYLATE FILM, NOVEL COMPOUND, POLARIZING PLATE AND LIQUID CRYSTAL DISPLAY DEVICE | NR1D1, NR1H2, NR1D2 | ALDH1A1 3058/4885HTT 4251/4885NPC1 456/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.