Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
| ▸ | CA7 | P43166 | 1/20 | 0.38 |
| ▸ | CA9 | Q16790 | 1/20 | 0.38 |
| ▸ | MAP3K14 | Q99558 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | MAPT | P10636 | 3/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | USP2 | O75604 | 2/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.33 |
| ▸ | THRB | P10828 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | BACE1 | P56817 | 2/20 | 0.33 |
| ▸ | HPGD | P15428 | 2/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.33 |
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2730653 | 0.84 | PTPN1 (0.34) | MAP3K14ALDH1A1MAPTALOX15HSD17B10 | |
| SCHEMBL17938771 | 0.80 | PLK1 (0.42) | MAP3K14ALDH1A1MAPTALOX15HSD17B10 | |
| SCHEMBL2107486 | 0.78 | TSHR (0.42) | CA1CA2CA7CA9MAP3K14 | |
| SCHEMBL20550365 | 0.72 | MAOA (0.45) | CA7ALDH1A1MAPTHSD17B10TDP1 | |
| SCHEMBL30689853 | 0.72 | CA1 (0.39) | CA1CA2CA7CA9ALDH1A1 | |
| SCHEMBL27882641 | 0.72 | CA1 (0.39) | CA1CA2CA7CA9ALDH1A1 | |
| SCHEMBL3698500 | 0.72 | CA1 (0.39) | CA1CA2CA7CA9ALDH1A1 | |
| SCHEMBL30543094 | 0.68 | CYP19A1 (0.46) | ALDH1A1MAPTTDP1MEN1KMT2A | |
| SCHEMBL31357424 | 0.68 | RIPK1 (0.50) | CA1CA2CA7CA9ALDH1A1 | |
| SCHEMBL726440 | 0.67 | CA1 (0.35) | CA1CA2CA7CA9ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1438424-B1 | ENZYME SUBSTRATES FOR DETECTING BETA-D-RIBOFURANOSIDASE ACTIVITY | BURTON MICHAEL (GB) | 2006-01-18 | — | — | EP | claimed |
| US-20040259181-A1 | detecting beta-D-ribofuranosidase activity using novel chromogenic beta-D-ribofuranoside substrates such as catechol-beta-D-ribofuranoside or 3',4'-dihydroxyflavone-4'-beta-D-dibofuranoside; kits | BURTON MICHAEL (GB) | 2004-12-23 | — | — | US | claimed |
| EP-1438424-A2 | ENZYME SUBSTRATES FOR DETECTING BETA-D-RIBOFURANOSIDASE ACTIVITY | Burton, Michael (GB) | 2004-07-21 | — | — | EP | claimed |
| WO-2003035897-A2 | ENZYME SUBSTRATES FOR DETECTING BETA-D-RIBOFURANOSIDASE ACTIVITY | BURTON MICHAEL (GB) | 2003-05-01 | — | — | WO | claimed |
| US-7709223-B2 | Method for detecting bacteria with chromogenic substrates for β-D-ribofuranosidase | BURTON MICHAEL | 2010-05-04 | — | — | US | disclosed |
| US-20080193959-A1 | Enzyme Substrates | BURTON MICHAEL | 2008-08-14 | — | — | US | disclosed |
| US-7384763-B2 | Method of detecting β-D-ribofuranosidase activity | BURTON MICHAEL | 2008-06-10 | — | — | US | disclosed |
| EP-1438424-B1 | ENZYME SUBSTRATES FOR DETECTING BETA-D-RIBOFURANOSIDASE ACTIVITY | BURTON MICHAEL (GB) | 2006-01-18 | — | — | EP | disclosed |
| US-20040259181-A1 | detecting beta-D-ribofuranosidase activity using novel chromogenic beta-D-ribofuranoside substrates such as catechol-beta-D-ribofuranoside or 3',4'-dihydroxyflavone-4'-beta-D-dibofuranoside; kits | BURTON MICHAEL (GB) | 2004-12-23 | — | — | US | disclosed |
| EP-1438424-A2 | ENZYME SUBSTRATES FOR DETECTING BETA-D-RIBOFURANOSIDASE ACTIVITY | Burton, Michael (GB) | 2004-07-21 | — | — | EP | disclosed |
| WO-2003035897-A2 | ENZYME SUBSTRATES FOR DETECTING BETA-D-RIBOFURANOSIDASE ACTIVITY | BURTON MICHAEL (GB) | 2003-05-01 | — | — | WO | disclosed |