Known targets — ChEMBL curated mechanism
KCNA1KCNA10KCNA2KCNA3KCNA4KCNA5KCNA6KCNA7KCNB1KCNB2KCNC1KCNC2KCNC3KCNC4KCND1KCND2KCND3KCNF1KCNG1KCNG2KCNG3KCNG4KCNH1KCNH2KCNH3KCNH4KCNH5KCNH6KCNH7KCNH8KCNQ1KCNQ2KCNQ3KCNQ4KCNQ5KCNS1KCNS2KCNS3KCNV1KCNV2
The experimentally established mechanism targets of Guanidine. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Guanidine SCHEMBL28264713 | 0.94 | — | — | |
| Guanidine SCHEMBL5613752 | 0.93 | — | — | |
| Guanidine SCHEMBL29983942 | 0.93 | — | — | |
| Guanidine SCHEMBL2003 | 0.93 | — | — | |
| Guanidine SCHEMBL11330173 | 0.93 | — | — | |
| Guanidine SCHEMBL165720 | 0.93 | NOS2 (0.42) | — | |
| Guanidine SCHEMBL25310528 | 0.86 | — | — | |
| Guanidine SCHEMBL19610646 | 0.86 | NOS2 (0.39) | — | |
| Guanidine SCHEMBL6274847 | 0.86 | — | — | |
| Guanidine SCHEMBL9110704 | 0.86 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 103 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12371774-B2 | Enhanced activation of self-passivating metals | SWAGELOK COMPANY (US) | 2025-07-29 | — | — | US | claimed |
| CN-112575284-B | Enhanced activation of self-passivating metals | 世伟洛克公司 | 2023-03-21 | — | — | CN | claimed |
| US-20230015135-A1 | ENHANCED ACTIVATION OF SELF-PASSIVATING METALS | CASE WESTERN RESERVE UNIVERSITY | 2023-01-19 | — | — | US | claimed |
| EP-4086366-A1 | ENHANCED ACTIVATION OF SELF-PASSIVATING METALS | Case Western Reserve University (US) | 2022-11-09 | — | — | EP | claimed |
| US-11473183-B2 | Enhanced activation of self-passivating metals | SWAGELOK COMPANY (US) | 2022-10-18 | — | — | US | claimed |
| EP-3175012-B1 | ENHANCED ACTIVATION OF SELF-PASSIVATING METALS | UNIV CASE WESTERN RESERVE (US) | 2022-06-15 | — | — | EP | claimed |
| CN-112575284-A | Enhanced activation of self-passivating metals | 世伟洛克公司 | 2021-03-30 | — | — | CN | claimed |
| CN-107109615-B | Enhanced activation of self-passivating metals | 世伟洛克公司 | 2020-12-04 | — | — | CN | claimed |
| US-20200283882-A1 | ENHANCED ACTIVATION OF SELF-PASSIVATING METALS | SWAGELOK COMPANY | 2020-09-10 | — | — | US | claimed |
| US-10604832-B2 | Enhanced activation of self-passivating metals | SWAGELOK COMPANY (US) | 2020-03-31 | — | — | US | claimed |
| US-20160032442-A1 | ENHANCED ACTIVATION OF SELF-PASSIVATING METALS | SWAGELOK COMPANY | 2016-02-04 | — | — | US | claimed |
| CN-103563154-A | Fluoride ion battery compositions | CONTOUR ENERGY SYSTEMS INC | 2014-02-05 | — | — | CN | claimed |
| EP-2338923-A1 | Polyurethane with a biocidal polyuric material as comonomer | Oberwalder, Sebastian (DE) | 2011-06-29 | — | — | EP | claimed |
| EP-2338342-A1 | Polyuric material with biocidal characteristics | Oberwalder, Sebastian (DE) | 2011-06-29 | — | — | EP | claimed |
| CN-102006773-A | Formulations and devices for delivering compounds to arthropods and microorganisms within arthopods | MEVLABS INC | 2011-04-06 | — | — | CN | claimed |
| US-7709656-B2 | Ionic liquids containing guanidinium cations | MERCK PATENT GMBH (DE) | 2010-05-04 | — | — | US | claimed |
| US-20070265453-A1 | Ionic Liquids Containing Guanidinium Cations | MERCK PATENT GMBH (DE) | 2007-11-15 | — | — | US | claimed |
| EP-1636173-A2 | IONIC LIQUIDS CONTAINING GUANIDINIUM CATIONS | MERCK PATENT GmbH (DE) | 2006-03-22 | — | — | EP | claimed |
| WO-2004106288-A2 | IONIC LIQUIDS CONTAINING GUANIDINIUM CATIONS | MERCK PATENT GMBH (DE) | 2004-12-09 | — | — | WO | claimed |
| US-3968158-A | FROM FLUORINE AND GUANIDINE OR SALTS | ROHM AND HAAS COMPANY (US) | 1976-07-06 | — | — | US | claimed |