Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13381654 | 0.81 | THRA (0.50) | THRATHRB | |
| SCHEMBL13044629 | 0.81 | THRA (0.65) | THRATHRB | |
| SCHEMBL23599477 | 0.69 | THRA (0.36) | THRATHRB | |
| SCHEMBL21291184 | 0.68 | THRA (0.49) | THRATHRB | |
| SCHEMBL23599568 | 0.67 | THRA (0.35) | THRATHRB | |
| SCHEMBL12642742 | 0.62 | THRB (0.75) | THRATHRB | |
| SCHEMBL13952400 | 0.60 | THRB (0.70) | THRATHRB | |
| SCHEMBL12584183 | 0.59 | THRA (1.00) | THRATHRB | |
| SCHEMBL21363742 | 0.59 | THRB (0.69) | THRATHRB | |
| SCHEMBL1581472 | 0.59 | THRA (0.58) | THRATHRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2428516-A1 | Novel phosphorus-containing thyromimetics | Metabasis Therapeutics, Inc. (US) | 2012-03-14 | — | — | EP | disclosed |