SCHEMBL3282950

SCHEMBL3282950

CCC[C@@H](NC(N)=O)C(=O)O

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
FPR2 P25090 1/20 0.46
CHRM1 P11229 1/20 0.44
AKR1A1 P14550 1/20 0.44
CHRM3 P20309 1/20 0.44
HTR2A P28223 1/20 0.44
HTR2C P28335 1/20 0.44
ADRA1A P35348 1/20 0.44
HRH1 P35367 1/20 0.44
DRD3 P35462 1/20 0.44
SLC6A3 Q01959 1/20 0.44
HDAC1 Q13547 1/20 0.44
HDAC2 Q92769 1/20 0.44
TDP1 Q9NUW8 1/20 0.44
NOD1 Q9Y239 4/20 0.43
FOLH1 Q04609 4/20 0.42
RIMKLA Q8IXN7 1/20 0.42
NAALAD2 Q9Y3Q0 1/20 0.42
MME P08473 1/20 0.42
CAD P27708 1/20 0.42
TGFBR1 P36897 2/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2172444 1.00 FPR2 (0.46) FPR2CHRM1AKR1A1CHRM3HTR2A
Hydrochloric Acid SCHEMBL32661728 0.98 FPR2 (0.45) FPR2CHRM1AKR1A1CHRM3HTR2A
SCHEMBL3282650 0.88 NOD1 (0.53) HDAC2NOD1FOLH1MMESLC1A3
SCHEMBL11254859 0.88 NOD1 (0.53) HDAC2NOD1FOLH1MMESLC1A3
SCHEMBL9953741 0.84 CAD (0.43) FPR2CHRM1AKR1A1CHRM3HTR2A
SCHEMBL8506897 0.84 NOD1 (0.58) NOD1GRIK1GRIK2SLC6A5MAPT
SCHEMBL2107300 0.83 FPR2 (0.44) FPR2CHRM1AKR1A1CHRM3HTR2A
SCHEMBL30678658 0.83 FPR2 (0.44) FPR2CHRM1AKR1A1CHRM3HTR2A
SCHEMBL18095235 0.83 CAD (0.40) FPR2CHRM1AKR1A1CHRM3HTR2A
Hydrochloric Acid SCHEMBL22534231 0.83 CAD (0.42) FPR2CHRM1AKR1A1CHRM3HTR2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7709235-B2 5-Substituted hydantoin racemase, DNA encoding the same, recombinant DNA, transformed cell, and process for production of optically active N-carbamylamino acid or optically active amino acid KANEKA CORPORATION (JP) 2010-05-04 US claimed
US-20080261268-A1 5-Substituted Hydantoin Racemase, Dna Encoding the Same, Recombinant Dna, Transformed Cell, and Process for Production of Optically Active N-Carbamylamino Acid or Optically Active Amino Acid KANEKA CORPORATION (JP) 2008-10-23 US claimed
EP-1852510-A1 5-SUBSTITUTED HYDANTOIN RACEMASE, DNA ENCODING THE SAME, RECOMBINANT DNA, TRANSFORMED CELL, AND PROCESS FOR PRODUCTION OF OPTICALLY ACTIVE N-CARBAMYLAMINO ACID OR OPTICALLY ACTIVE AMINO ACID Kaneka Corporation (JP) 2007-11-07 EP claimed
WO-2023174511-A1 ENZYMATIC METHOD FOR THE PRODUCTION OF L-GLUFOSINATE P-ESTERS EVONIK OPERATIONS GMBH (DE) 2023-09-21 WO disclosed
US-7709235-B2 5-Substituted hydantoin racemase, DNA encoding the same, recombinant DNA, transformed cell, and process for production of optically active N-carbamylamino acid or optically active amino acid KANEKA CORPORATION (JP) 2010-05-04 US disclosed
US-20080261268-A1 5-Substituted Hydantoin Racemase, Dna Encoding the Same, Recombinant Dna, Transformed Cell, and Process for Production of Optically Active N-Carbamylamino Acid or Optically Active Amino Acid KANEKA CORPORATION (JP) 2008-10-23 US disclosed
EP-1852510-A1 5-SUBSTITUTED HYDANTOIN RACEMASE, DNA ENCODING THE SAME, RECOMBINANT DNA, TRANSFORMED CELL, AND PROCESS FOR PRODUCTION OF OPTICALLY ACTIVE N-CARBAMYLAMINO ACID OR OPTICALLY ACTIVE AMINO ACID Kaneka Corporation (JP) 2007-11-07 EP disclosed