Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL328461 | 0.85 | THRB (0.47) | THRBTHRA | |
| SCHEMBL282522 | 0.84 | THRA (0.70) | THRBTHRA | |
| SCHEMBL13381715 | 0.83 | THRB (0.60) | THRBTHRA | |
| SCHEMBL27645304 | 0.81 | THRB (0.57) | THRBTHRA | |
| SCHEMBL4203861 | 0.76 | THRB (0.64) | THRBTHRA | |
| SCHEMBL4198484 | 0.76 | THRB (0.55) | THRBTHRA | |
| SCHEMBL13557778 | 0.75 | THRB (0.52) | THRBTHRA | |
| SCHEMBL3160844 | 0.75 | THRB (0.71) | THRBTHRA | |
| SCHEMBL18781787 | 0.74 | THRA (0.61) | THRBTHRA | |
| SCHEMBL283233 | 0.74 | THRA (0.74) | THRBTHRA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2428516-A1 | Novel phosphorus-containing thyromimetics | Metabasis Therapeutics, Inc. (US) | 2012-03-14 | — | — | EP | disclosed |