Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL328340 | 0.85 | THRB (0.52) | THRBTHRA | |
| SCHEMBL282236 | 0.83 | THRA (0.65) | THRBTHRA | |
| SCHEMBL13557769 | 0.83 | THRB (0.46) | THRBTHRA | |
| SCHEMBL13381736 | 0.82 | THRA (0.55) | THRBTHRA | |
| SCHEMBL5137059 | 0.81 | THRA (0.50) | THRBTHRA | |
| SCHEMBL3888472 | 0.81 | THRA (0.53) | THRBTHRA | |
| SCHEMBL282335 | 0.78 | THRA (0.67) | THRBTHRA | |
| SCHEMBL27666391 | 0.78 | THRB (0.50) | THRBTHRA | |
| SCHEMBL13557778 | 0.78 | THRB (0.52) | THRBTHRA | |
| SCHEMBL13381720 | 0.77 | THRA (0.57) | THRBTHRA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2428516-A1 | Novel phosphorus-containing thyromimetics | Metabasis Therapeutics, Inc. (US) | 2012-03-14 | — | — | EP | disclosed |