Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPA1 | O75762 | 1/20 | 0.60 |
| ▸ | ABL1 | P00519 | 1/20 | 0.59 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.59 |
| ▸ | BCR | P11274 | 1/20 | 0.59 |
| ▸ | AR | P10275 | 2/20 | 0.55 |
| ▸ | ERN1 | O75460 | 1/20 | 0.53 |
| ▸ | MAOB | P27338 | 1/20 | 0.51 |
| ▸ | GAA | P10253 | 2/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.49 |
| ▸ | PLAU | P00749 | 1/20 | 0.47 |
| ▸ | PLAT | P00750 | 1/20 | 0.47 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.46 |
| ▸ | HNF4A | P41235 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3284015 | 1.00 | TRPA1 (0.60) | TRPA1ABL1ABCB1BCRAR | |
| SCHEMBL331513 | 0.89 | ABL1 (0.63) | TRPA1ABL1ABCB1BCRAR | |
| SCHEMBL331511 | 0.89 | ABL1 (0.63) | TRPA1ABL1ABCB1BCRAR | |
| SCHEMBL27473548 | 0.85 | TRPA1 (0.60) | TRPA1ABL1ABCB1BCRAR | |
| SCHEMBL23612301 | 0.83 | ERN1 (0.55) | TRPA1ABL1ABCB1BCRAR | |
| SCHEMBL11103387 | 0.82 | TRPA1 (0.67) | TRPA1PTPN1HNF4AKDM4E | |
| SCHEMBL11103388 | 0.82 | TRPA1 (0.67) | TRPA1PTPN1HNF4AKDM4E | |
| SCHEMBL27817127 | 0.82 | KMT2A (0.57) | ABL1ABCB1BCRERN1GAA | |
| SCHEMBL901262 | 0.81 | ERN1 (0.53) | ABL1ABCB1BCRARERN1 | |
| SCHEMBL901263 | 0.81 | ERN1 (0.53) | ABL1ABCB1BCRARERN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0049126-A1 | Alpha-methyl-benzyl-chlorophenols and process for their preparation | COALITE GROUP LIMITED (GB) | 1982-04-07 | — | — | EP | claimed |
| US-7700655-B2 | Antiallergic agents | INSTITUTE OF MEDICINAL MOLECULAR DESIGN, INC. (JP) | 2010-04-20 | — | — | US | disclosed |
| US-20080090779-A1 | ANTIALLERGIC AGENTS | INSTITUTE OF MEDICINAL MOLECULAR DESIGN, INC. (JP) | 2008-04-17 | — | — | US | disclosed |
| US-20070185059-A1 | Antiallergic agents | INSTITUTE OF MEDICINAL MOLECULAR DESIGN, INC. (JP) | 2007-08-09 | — | — | US | disclosed |
| US-20070185110-A1 | Antiallergic agents | INSTITUTE OF MEDICINAL MOLECULAR DESIGN, INC. (JP) | 2007-08-09 | — | — | US | disclosed |
| US-20060122243-A1 | Antiallergic | INSTITUTE OF MEDICINAL MOLECULAR DESIGN, INC. (JP) | 2006-06-08 | — | — | US | disclosed |
| US-20060100257-A1 | Inhibitors against the activation of ap-1 and nfat | INSTITUTE OF MEDICINAL MOLECULAR DESIGN, INC. (JP) | 2006-05-11 | — | — | US | disclosed |
| EP-0049126-A1 | Alpha-methyl-benzyl-chlorophenols and process for their preparation | COALITE GROUP LIMITED (GB) | 1982-04-07 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080090779-A1 | ANTIALLERGIC AGENTS | NAT1, EPX, HRH2 | TRPA1 81/4885ABL1 4615/4885ABCB1 1721/4885 |
| US-20060122243-A1 | Antiallergic | EPX, NAT1, HNMT | TRPA1 135/4885ABL1 4542/4885ABCB1 1824/4885 |
| US-20060100257-A1 | Inhibitors against the activation of ap-1 and nfat | NFATC1, AP1G1, ATF1 | TRPA1 1159/4885ABL1 1451/4885ABCB1 1919/4885 |
| US-20070185110-A1 | Antiallergic agents | NAT1, EPX, AHR | TRPA1 98/4885ABL1 4581/4885ABCB1 1835/4885 |
| US-20070185059-A1 | Antiallergic agents | NAT1, EPX, AHR | TRPA1 102/4885ABL1 4553/4885ABCB1 1864/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.