Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 4/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
| ▸ | PGD | P52209 | 1/20 | 0.31 |
| ▸ | LPAR3 | Q9UBY5 | 3/20 | 0.31 |
| ▸ | LPAR1 | Q92633 | 2/20 | 0.31 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27838293 | 0.92 | TSHR (0.36) | TSHRCYP3A4L3MBTL1ALDH1A1THRB | |
| SCHEMBL2638511 | 0.88 | PGD (0.42) | TSHRPGDLPAR3LPAR1ENPP2 | |
| SCHEMBL2639660 | 0.88 | TSHR (0.38) | TSHRALDH1A1THRBPGDLPAR3 | |
| SCHEMBL898473 | 0.85 | LPAR3 (0.39) | TSHRALDH1A1THRBPGDLPAR3 | |
| SCHEMBL8599613 | 0.85 | TSHR (0.50) | TSHRCYP3A4L3MBTL1ALDH1A1THRB | |
| SCHEMBL17350444 | 0.84 | TSHR (0.35) | TSHRALDH1A1THRB | |
| SCHEMBL24549483 | 0.82 | L3MBTL1 (0.38) | L3MBTL1ALDH1A1 | |
| SCHEMBL440616 | 0.81 | TSHR (0.45) | TSHRALDH1A1THRB | |
| SCHEMBL158386 | 0.80 | TSHR (0.57) | TSHRALDH1A1THRB | |
| SCHEMBL17947770 | 0.80 | TSHR (0.42) | TSHRALDH1A1THRBLPAR3LPAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7700668-B2 | Adhesive composition with decreased polarity upon polymerization | 3M ESPE AG (DE) | 2010-04-20 | — | — | US | claimed |
| US-20060270751-A1 | Adhesive composition with decreased polarity upon polymerization | 3M DEUTSCHLAND GMBH (DE) | 2006-11-30 | — | — | US | claimed |
| EP-1498098-B1 | Adhesive composition with decreased polarity upon polymerization | 3M ESPE AG (DE) | 2006-05-03 | — | — | EP | claimed |
| EP-1498098-A1 | Adhesive composition with decreased polarity upon polymerization | 3M ESPE AG (DE) | 2005-01-19 | — | — | EP | claimed |
| US-7700668-B2 | Adhesive composition with decreased polarity upon polymerization | 3M ESPE AG (DE) | 2010-04-20 | — | — | US | disclosed |
| EP-1639987-B1 | Dental adhesive composition | 3M ESPE AG (DE) | 2009-08-12 | — | — | EP | disclosed |
| US-20060270751-A1 | Adhesive composition with decreased polarity upon polymerization | 3M DEUTSCHLAND GMBH (DE) | 2006-11-30 | — | — | US | disclosed |
| EP-1498098-B1 | Adhesive composition with decreased polarity upon polymerization | 3M ESPE AG (DE) | 2006-05-03 | — | — | EP | disclosed |
| US-20060069181-A1 | Dental adhesive composition | 3M ESPE AG | 2006-03-30 | — | — | US | disclosed |
| EP-1639987-A1 | Dental adhesive composition | 3M Espe AG (DE) | 2006-03-29 | — | — | EP | disclosed |
| WO-2005004819-A1 | ADHESIVE COMPOSITION WITH DECREASED POLARITY UPON POLYMERIZATION | 3M ESPE AG (DE) | 2005-01-20 | — | — | WO | disclosed |
| EP-1498098-A1 | Adhesive composition with decreased polarity upon polymerization | 3M ESPE AG (DE) | 2005-01-19 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060270751-A1 | Adhesive composition with decreased polarity upon polymerization | PTK2, PHOSPHO1, ITGA1 | TSHR 4650/4885CYP3A4 4432/4885L3MBTL1 3030/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.