Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.41 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.41 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.41 |
| ▸ | ALDH3A1 | P30838 | 2/20 | 0.40 |
| ▸ | ALDH1A3 | P47895 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | CRHR1 | P34998 | 9/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | CASP1 | P29466 | 1/20 | 0.32 |
| ▸ | BRCA1 | P38398 | 1/20 | 0.32 |
| ▸ | CASP7 | P55210 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13459218 | 0.83 | ALDH3A1 (0.40) | CSNK2A2CSNK2BCSNK2A1ALDH3A1ALDH1A3 | |
| SCHEMBL13459549 | 0.80 | AR (0.37) | CSNK2A2CSNK2BCSNK2A1CRHR1 | |
| SCHEMBL3288733 | 0.74 | HTR1A (0.44) | CRHR1RAB9A | |
| SCHEMBL13459221 | 0.72 | CSNK2A2 (0.37) | CSNK2A2CSNK2BCSNK2A1ALDH1A1CRHR1 | |
| SCHEMBL13459535 | 0.71 | POLB (0.40) | CSNK2A2CSNK2BCSNK2A1ALDH1A1CRHR1 | |
| SCHEMBL2085120 | 0.71 | CSNK2A2 (0.42) | CSNK2A2CSNK2BCSNK2A1ALDH1A1CRHR1 | |
| SCHEMBL3285073 | 0.68 | CRHR1 (0.42) | ALDH3A1ALDH1A3ALDH1A1CRHR1 | |
| SCHEMBL13459223 | 0.67 | CRHR1 (0.38) | CSNK2A2CSNK2BCSNK2A1ALDH3A1ALDH1A3 | |
| SCHEMBL13459581 | 0.66 | POLB (0.36) | CSNK2A2CSNK2BCSNK2A1ALDH1A1CRHR1 | |
| SCHEMBL3285011 | 0.65 | TSHR (0.43) | MEN1KMT2ASMN1; SMN2CYP1A2RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7714009-B2 | Nitrogen-containing fused heterocyclic compounds | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2010-05-11 | — | — | US | disclosed |
| US-20070135452-A1 | Nitrogen-containing fused heterocyclic compounds | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2007-06-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070135452-A1 | Nitrogen-containing fused heterocyclic compounds | NPY4R, NR4A3, NR3C2 | CSNK2A2 460/4885CSNK2B 433/4885CSNK2A1 435/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.