Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 15/20 | 0.67 |
| ▸ | THRA | P10827 | 14/20 | 0.67 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.40 |
| ▸ | ADRA2B | P18089 | 2/20 | 0.40 |
| ▸ | ADRA2C | P18825 | 2/20 | 0.40 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.40 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.38 |
| ▸ | ADRB3 | P13945 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL282702 | 0.92 | THRA (0.69) | THRBTHRAADRA2AADRA2BADRA2C | |
| SCHEMBL13381700 | 0.82 | THRA (0.56) | THRBTHRAADRA2AADRA2BADRA2C | |
| SCHEMBL22071770 | 0.82 | THRA (0.55) | THRBTHRAADRA2AADRA2BADRA2C | |
| SCHEMBL3147737 | 0.81 | THRB (0.74) | THRBTHRAPTPN1 | |
| SCHEMBL10274395 | 0.81 | THRB (1.00) | THRBTHRAPTPN1 | |
| SCHEMBL3161475 | 0.79 | THRB (0.67) | THRBTHRA | |
| SCHEMBL21565819 | 0.79 | THRB (0.67) | THRBTHRAPTPN1 | |
| SCHEMBL4962963 | 0.79 | THRB (0.69) | THRBTHRAPTPN1 | |
| SCHEMBL282585 | 0.78 | THRB (0.65) | THRBTHRAPTPN1 | |
| SCHEMBL282128 | 0.78 | THRB (0.79) | THRBTHRAPTPN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2428516-A1 | Novel phosphorus-containing thyromimetics | Metabasis Therapeutics, Inc. (US) | 2012-03-14 | — | — | EP | disclosed |