Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.41 |
| ▸ | CYP2A6 | P11509 | 3/20 | 0.40 |
| ▸ | ALDH5A1 | P51649 | 1/20 | 0.40 |
| ▸ | ABAT | P80404 | 1/20 | 0.40 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.40 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | ALDH3A1 | P30838 | 1/20 | 0.38 |
| ▸ | ALDH1A3 | P47895 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | NOS1 | P29475 | 1/20 | 0.38 |
| ▸ | EGFR | P00533 | 1/20 | 0.37 |
| ▸ | TYR | P14679 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | CYP2A13 | Q16696 | 1/20 | 0.36 |
| ▸ | IDO1 | P14902 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3286279 | 0.90 | EPHX2 (0.47) | ALDH1A1CYP2A6EPHX2NR1H4LMNA | |
| SCHEMBL4273816 | 0.90 | FFAR1 (0.42) | ALDH1A1EPHX2NR1H4LMNAMAPT | |
| SCHEMBL6537071 | 0.83 | ALDH1A1 (0.41) | ALDH1A1LMNAMAPTNOS1IDO1 | |
| SCHEMBL4267757 | 0.81 | NPC1 (0.40) | ALDH1A1CYP2A6ALDH5A1ABATEPHX2 | |
| SCHEMBL4262310 | 0.79 | ALDH1A1 (0.38) | ALDH1A1CYP2A6ALDH5A1ABATEPHX2 | |
| SCHEMBL3286710 | 0.79 | UNG (0.43) | ALDH1A1NOS1IDO1 | |
| SCHEMBL6517369 | 0.78 | IDO1 (0.59) | ALDH1A1CYP2A6LMNAMAPTSMN1; SMN2 | |
| SCHEMBL11957418 | 0.78 | NOS1 (0.46) | ALDH1A1KMT2ANOS1IDO1 | |
| SCHEMBL10126371 | 0.78 | IDO1 (0.51) | ALDH1A1LMNAKMT2ANOS1KDM4E | |
| SCHEMBL19725955 | 0.78 | IDO1 (0.59) | ALDH1A1HPGDSMN1; SMN2NOS1EGFR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7022862-B2 | Scalable synthesis of dipyrromethanes | NORTH CAROLINA STATE UNIVERSITY (US) | 2006-04-04 | — | — | US | claimed |
| US-20050038262-A1 | aldehyde-pyrrole catalytic condensation leading to dipyrromethanes as a crystalline solid or as intermediates used for making porphyrin compounds; non-aqueous process | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2005-02-17 | — | — | US | claimed |
| US-7718794-B2 | Synthesis of porphyrins designed for attachment to electroactive surfaces via one or more carbon tethers | NORTH CAROLINA STATE UNIVERSITY (US) | 2010-05-18 | — | — | US | disclosed |
| US-7518905-B2 | High density memory device | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2009-04-14 | — | — | US | disclosed |
| US-20080194839-A1 | SYNTHESIS OF PORPHYRINS DESIGNED FOR ATTACHMENT TO ELECTROACTIVE SURFACES VIA ONE OR MORE CARBON TETHERS | NORTH CAROLINA STATE UNIVERSITY (US) | 2008-08-14 | — | — | US | disclosed |
| US-7378520-B2 | Synthesis of porphyrins designed for attachment to electroactive surfaces via one or more carbon tethers | NORTH CAROLINA STATE UNIVERSITY (US) | 2008-05-27 | — | — | US | disclosed |
| EP-1763317-A1 | SYNTHESIS OF PORPHYRINS DESIGNED FOR ATTACHMENT TO ELECTROACTIVE SURFACES VIA ONE OR MORE CARBON TETHERS | North Carolina State University (US) | 2007-03-21 | — | — | EP | disclosed |
| US-20060209587-A1 | High density memory device | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA | 2006-09-21 | — | — | US | disclosed |
| US-7042755-B1 | High density non-volatile memory device | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA | 2006-05-09 | — | — | US | disclosed |
| US-7022862-B2 | Scalable synthesis of dipyrromethanes | NORTH CAROLINA STATE UNIVERSITY (US) | 2006-04-04 | — | — | US | disclosed |
| WO-2006016943-A1 | SYNTHESIS OF PORPHYRINS DESIGNED FOR ATTACHMENT TO ELECTROACTIVE SURFACES VIA ONE OR MORE CARBON TETHERS | NORTH CAROLINA STATE UNIVERSITY (US) | 2006-02-16 | — | — | WO | disclosed |
| US-20060009638-A1 | Synthesis of porphyrins designed for attachment to electroactive surfaces via one or more carbon tethers | ZETTACORE, INC. | 2006-01-12 | — | — | US | disclosed |
| US-20050038262-A1 | aldehyde-pyrrole catalytic condensation leading to dipyrromethanes as a crystalline solid or as intermediates used for making porphyrin compounds; non-aqueous process | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2005-02-17 | — | — | US | disclosed |
| WO-2001003126-A9 | HIGH DENSITY NON-VOLATILE MEMORY DEVICE | UNIV CALIFORNIA (US) | 2002-08-01 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060009638-A1 | Synthesis of porphyrins designed for attachment to electroactive surfaces via one or more carbon tethers | SCO2, PPOX, HCCS | ALDH1A1 909/4885CYP2A6 819/4885ALDH5A1 210/4885 |
| US-20050038262-A1 | aldehyde-pyrrole catalytic condensation leading to dipyrromethanes as a crystalline solid or as intermediates used for making porphyrin compounds; non-aqueous process | PPOX, DAO, DDO | ALDH1A1 72/4885CYP2A6 895/4885ALDH5A1 20/4885 |
| US-20080194839-A1 | SYNTHESIS OF PORPHYRINS DESIGNED FOR ATTACHMENT TO ELECTROACTIVE SURFACES VIA ONE OR MORE CARBON TETHERS | SCO2, PPOX, HCCS | ALDH1A1 909/4885CYP2A6 819/4885ALDH5A1 210/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.