SCHEMBL3286254

SCHEMBL3286254

CCCOC(=N)c1ccccc1

nearest known ligand 0.60

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.60
ALDH1A1 P00352 6/20 0.47
HPGD P15428 4/20 0.46
GAA P10253 2/20 0.41
SMN1; SMN2 Q16637 1/20 0.41
TDP1 Q9NUW8 2/20 0.40
ELANE P08246 1/20 0.40
ESR1 P03372 1/20 0.40
CHRM1 P11229 1/20 0.40
TSHR P16473 1/20 0.40
SLC6A2 P23975 1/20 0.40
KDR P35968 1/20 0.40
KMT2A Q03164 3/20 0.40
HTT P42858 1/20 0.39
MEN1 O00255 2/20 0.39
MAPT P10636 1/20 0.39
THRB P10828 1/20 0.39
POLB P06746 1/20 0.38
NPSR1 Q6W5P4 1/20 0.38
CES2 O00748 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3287503 0.88 TSHR (0.50) LMNAALDH1A1HPGDSMN1; SMN2TDP1
SCHEMBL29130134 0.86 TSHR (0.51) LMNAALDH1A1TDP1TSHRPOLB
SCHEMBL3283312 0.85 TSHR (0.53) LMNAALDH1A1SMN1; SMN2TDP1TSHR
SCHEMBL437904 0.83 DGAT1 (0.52) LMNAALDH1A1GAASMN1; SMN2TSHR
Hydrochloric Acid SCHEMBL6645105 0.81 LMNA (0.41) LMNAALDH1A1SMN1; SMN2TDP1TSHR
Hydrochloric Acid SCHEMBL336974 0.81 DGAT1 (0.50) LMNAALDH1A1GAASMN1; SMN2TSHR
SCHEMBL27634820 0.80 LMNA (0.39) LMNAALDH1A1HPGDSMN1; SMN2TDP1
Hydrochloric Acid SCHEMBL6960112 0.79 DGAT1 (0.49) LMNAALDH1A1GAASMN1; SMN2TSHR
SCHEMBL1449661 0.78 LMNA (0.64) LMNAALDH1A1HPGDGAASMN1; SMN2
SCHEMBL2253649 0.78 LMNA (0.64) LMNAALDH1A1HPGDGAASMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7705175-B2 Method for producing imide ether compound NIPPOH CHEMICALS CO., LTD. (JP) 2010-04-27 US disclosed
US-20090005599-A1 Method for Producing Imide Ether Compound NIPPOH CHEMICALS CO., LTD. (JP) 2009-01-01 US disclosed