SCHEMBL437904

SCHEMBL437904

CCOC(=N)c1ccccc1

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
DGAT1 O75907 1/20 0.52
MAPT P10636 3/20 0.47
MEN1 O00255 3/20 0.47
KMT2A Q03164 3/20 0.47
NPC1 O15118 2/20 0.47
ALDH1A1 P00352 2/20 0.47
LMNA P02545 1/20 0.44
TSHR P16473 1/20 0.43
SMN1; SMN2 Q16637 3/20 0.42
GAA P10253 3/20 0.42
RAB9A P51151 1/20 0.42
F2 P00734 1/20 0.41
F10 P00742 1/20 0.41
F12 P00748 1/20 0.41
F7 P08709 1/20 0.41
F3 P13726 1/20 0.41
PKM P14618 1/20 0.41
ATM Q13315 1/20 0.40
PIN1 Q13526 1/20 0.40
POLB P06746 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL336974 0.98 DGAT1 (0.50) DGAT1MAPTMEN1KMT2ANPC1
Hydrochloric Acid SCHEMBL6960112 0.96 DGAT1 (0.49) DGAT1MAPTMEN1KMT2ANPC1
SCHEMBL13108706 0.88 DGAT1 (0.62) DGAT1MEN1KMT2AALDH1A1LMNA
SCHEMBL11174091 0.88 DGAT1 (0.50) DGAT1MAPTMEN1KMT2AALDH1A1
SCHEMBL13108721 0.86 DGAT1 (0.52) DGAT1MAPTMEN1KMT2ANPC1
Hydrochloric Acid SCHEMBL3736474 0.86 DGAT1 (0.49) DGAT1MAPTMEN1KMT2AALDH1A1
Hydrochloric Acid SCHEMBL17512889 0.86 DGAT1 (0.60) DGAT1MEN1KMT2AALDH1A1LMNA
Hydrochloric Acid SCHEMBL20766398 0.86 DGAT1 (0.60) DGAT1MEN1KMT2AALDH1A1LMNA
SCHEMBL3739816 0.85 LTA4H (0.53) DGAT1MAPTNPC1ALDH1A1LMNA
Hydrochloric Acid SCHEMBL3739815 0.83 LTA4H (0.52) DGAT1MAPTNPC1ALDH1A1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 230 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115710227-A Preparation method of indenoisoquinoline derivative 广东工业大学 2023-02-24 CN claimed
CN-114295741-A Method for simultaneously quantifying travoprost and travoprost acid contained in solution sample 沈阳兴齐眼药股份有限公司 2022-04-08 CN claimed
CN-113912519-B Crystal form B of 2-cyano-3-amino-3-ethyl phenylacrylate, preparation method and application 江苏省农药研究所股份有限公司 2022-03-08 CN claimed
CN-113402424-A Synthetic method of cyanoacrylate compound 上海泰初化工技术有限公司 2021-09-17 CN claimed
EP-4737470-A2 C10-ALKYLENE SUBSTITUTED 13-MEMBERED MACROLIDES AND USES THEREOF Zikani Therapeutics, Inc. (US) 2026-05-06 EP disclosed
US-12552825-B2 C10-alkylene substituted 13-membered macrolides and uses thereof Zikani Therapeutics , Inc. (US) 2026-02-17 US disclosed
EP-3883647-B1 C10-ALKYLENE SUBSTITUTED 13-MEMBERED MACROLIDES AND USES THEREOF ZIKANI THERAPEUTICS INC (US) 2026-02-11 EP disclosed
US-20260035402-A1 C10-ALKYLENE SUBSTITUTED 13-MEMBERED MACROLIDES AND USES THEREOF ZIKANI THERAPEUTICS INC (US) 2026-02-05 US disclosed
US-12404221-B2 Methods of arene alkenylation UNIVERSITY OF VIRGINIA PATENT FOUNDATION (US) 2025-09-02 US disclosed
US-20250223306-A1 TEAD INHIBITORS AND METHODS OF USE SPOROS BIOVENTURES, INC., 2025-07-10 US disclosed
US-20250188072-A1 COMPOUNDS FOR TREATMENT OF CANCER UNIVERSITY OF TENNESSEE RESEARCH FOUNDATION (US) 2025-06-12 US disclosed
EP-4496789-A1 TEAD INHIBITORS AND METHODS OF USE Sporos Biodiscovery, Inc. (US) 2025-01-29 EP disclosed
EP-0810858-A2 BORONIC ACID AND ESTER INHIBITORS OF THROMBIN THE DU PONT MERCK PHARMACEUTICAL COMPANY (US) 1997-12-10 EP disclosed
US-5563127-A USEFUL TO TREAT THROMBOSIS THE DUPONT MERCK PHARMACEUTICAL COMPANY (US) 1996-10-08 US disclosed
WO-1996020689-A2 BORONIC ACID AND ESTER INHIBITORS OF THROMBIN THE DU PONT MERCK PHARMACEUTICAL COMPANY (US) 1996-07-11 WO disclosed
EP-0080053-B1 3,5-DIPHENYL-1H-1,2,4-TRIAZOLES WITH CONTRAGESTATIONAL ACTIVITY, PHARMACEUTICAL COMPOSITIONS THEREOF AND PROCESS FOR THEIR PREPARATION GRUPPO LEPETIT S.P.A. (IT) 1986-03-05 EP disclosed
US-4535090-A ANTIFERTILITY AGENTS; ABORTION GRUPPO LEPETIT S.P.A. (IT) 1985-08-13 US disclosed
EP-0080053-A1 3,5-Diphenyl-1H-1,2,4-triazoles with contragestational activity, pharmaceutical compositions thereof and process for their preparation GRUPPO LEPETIT S.P.A. (IT) 1983-06-01 EP disclosed
US-4379155-A 3,5-Disubstituted-1H-1,2,4-triazole derivatives GRUPPO LEPETIT S.P.A. (IT) 1983-04-05 US disclosed
US-4370336-A OXYTOCICS GRUPPO LEPETIT S.P.A. (IT) 1983-01-25 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260035402-A1 C10-ALKYLENE SUBSTITUTED 13-MEMBERED MACROLIDES AND USES THEREOF MALT1, CCR10, CYP51A1 DGAT1 903/4885MAPT 4810/4885MEN1 3251/4885
US-12552825-B2 C10-alkylene substituted 13-membered macrolides and uses thereof MALT1, NR3C2, MRPL21 DGAT1 698/4885MAPT 4658/4885MEN1 2487/4885
US-12404221-B2 Methods of arene alkenylation CYBB, CBR3, AHR DGAT1 2474/4885MAPT 4342/4885MEN1 4381/4885
US-20250223306-A1 TEAD INHIBITORS AND METHODS OF USE TEAD1, TEAD2, TEAD3 DGAT1 1063/4885MAPT 2193/4885MEN1 4168/4885
US-20250188072-A1 COMPOUNDS FOR TREATMENT OF CANCER KLK3, BRDT, ACP3 DGAT1 1779/4885MAPT 2614/4885MEN1 165/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.