SCHEMBL3286344

SCHEMBL3286344

O=[N+]([O-])C1([N+](=O)[O-])COC1

nearest known ligand 0.36

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
KCNA4 P22459 1/20 0.36
KCNA1 Q09470 1/20 0.36
KCNAB1 Q14722 1/20 0.36
NLRP3 Q96P20 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12045567 0.73 KCNA4 (0.31) KCNA4KCNA1KCNAB1
SCHEMBL3287242 0.73 KCNA4 (0.61) KCNA4KCNA1KCNAB1
SCHEMBL11422486 0.71
SCHEMBL14911002 0.69
SCHEMBL272478 0.69 NLRP3 (0.36) NLRP3
SCHEMBL3285840 0.65 NLRP3 (0.33) NLRP3
SCHEMBL3289507 0.62 NLRP3 (0.32) NLRP3
SCHEMBL3298482 0.62 NLRP3 (0.32) NLRP3
Dioxane SCHEMBL5805799 0.60 CA5A (0.57)
Dioxane SCHEMBL27608979 0.60 TTR (0.43)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7713401-B2 Methods for performing electrochemical nitration reactions BATTELLE ENERGY ALLIANCE, LLC (US) 2010-05-11 US disclosed
US-20090038953-A1 METHODS FOR PERFORMING ELECTROCHEMICAL NITRATION REACTIONS ENERGY, UNITED STATES DEPARTMENT OF 2009-02-12 US disclosed
WO-2009020798-A1 METHODS FOR PERFORMING ELECTROCHEMICAL NITRATION REACTIONS BATTELLE ENERGY ALLIANCE, LLC (US) 2009-02-12 WO disclosed
US-4910322-A Synthesis of geminal dinitro compounds THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE AIR FORCE (US) 1990-03-20 US disclosed
US-4774366-A Synthesis of geminal dinitro compounds THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE AIR FORCE (US) 1988-09-27 US disclosed
US-4594430-A Synthesis of geminal dinitro compounds UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE AIR FORCE (US) 1986-06-10 US disclosed