Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 3/20 | 0.69 |
| ▸ | DRD4 | P21917 | 2/20 | 0.69 |
| ▸ | PARP1 | P09874 | 1/20 | 0.51 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.51 |
| ▸ | DRD1 | P21728 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | ABL1 | P00519 | 1/20 | 0.48 |
| ▸ | ALPL | P05186 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | RIN1 | Q13671 | 1/20 | 0.48 |
| ▸ | MTNR1B | P49286 | 2/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9416632 | 0.84 | DRD2 (0.72) | DRD2DRD1MTNR1BCYP3A4CYP2D6 | |
| SCHEMBL13356020 | 0.82 | DRD2 (1.00) | DRD2DRD4PARP1ALOX15HSD17B10 | |
| SCHEMBL29617590 | 0.82 | DRD2 (1.00) | DRD2DRD4PARP1ALOX15HSD17B10 | |
| SCHEMBL16625803 | 0.79 | MTNR1B (0.47) | DRD2DRD4DRD1MEN1KMT2A | |
| SCHEMBL13064945 | 0.78 | LMNA (0.68) | HSD17B10MEN1KMT2AMTNR1BCYP3A4 | |
| SCHEMBL31538834 | 0.78 | LMNA (0.68) | HSD17B10MEN1KMT2AMTNR1BCYP3A4 | |
| SCHEMBL3506766 | 0.77 | MTNR1B (0.69) | DRD2DRD1MEN1KMT2AMTNR1B | |
| SCHEMBL16627051 | 0.77 | MTNR1B (0.61) | DRD2DRD1MEN1KMT2AMTNR1B | |
| SCHEMBL9637922 | 0.74 | LMNA (0.61) | HSD17B10MEN1KMT2AMTNR1BCYP3A4 | |
| SCHEMBL18179207 | 0.72 | DRD2 (0.89) | DRD2DRD4ALOX15HSD17B10DRD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8912332-B2 | Synthesis of trivalent flexible frameworks with ligands comprising catechol units for functionalizing surfaces | JUSTUS-LIEBIG-UNIVERSITAET GIESSEN (DE) | 2014-12-16 | — | — | US | disclosed |
| US-8912332-B2 | Synthesis of trivalent flexible frameworks with ligands comprising catechol units for functionalizing surfaces | JUSTUS-LIEBIG-UNIVERSITAET GIESSEN (DE) | 2014-12-16 | — | — | US | disclosed |
| EP-2428502-B1 | Synthesis of tripodal catechol derivatives with an adamantyl base for functionalising surfaces | Justus Liebig Universität Giessen (DE) | 2014-12-10 | — | — | EP | disclosed |
| EP-2428503-B1 | Synthesis of tripodal catechol derivatives with a flexible base for functionalising surfaces | Justus Liebig Universität Giessen (DE) | 2014-12-10 | — | — | EP | disclosed |
| US-8785641-B2 | Synthesis of tripodal catechol derivatives having an adamantyl basic framework for functionalizing surfaces | JUSTUS-LIEBIG-UNIVERSITAT GIESSEN (DE) | 2014-07-22 | — | — | US | disclosed |
| US-8785641-B2 | Synthesis of tripodal catechol derivatives having an adamantyl basic framework for functionalizing surfaces | JUSTUS-LIEBIG-UNIVERSITAT GIESSEN (DE) | 2014-07-22 | — | — | US | disclosed |
| US-20130245270-A1 | Synthesis of Trivalent Flexible Frameworks with Ligands Comprising Catechol Units for Functionalizing Surfaces | JUSTUS-LIEBIG-UNIVERSITAT GIESSEN (DE) | 2013-09-19 | — | — | US | disclosed |
| US-20130245269-A1 | Synthesis of Tripodal Catechol Derivatives Having an Adamantyl Basic Framework for Functionalizing Surfaces | JUSTUS-LIEBIG-UNIVERSITA GIESSEN (DE) | 2013-09-19 | — | — | US | disclosed |
| US-20130245269-A1 | Synthesis of Tripodal Catechol Derivatives Having an Adamantyl Basic Framework for Functionalizing Surfaces | JUSTUS-LIEBIG-UNIVERSITA GIESSEN (DE) | 2013-09-19 | — | — | US | disclosed |
| US-20130245270-A1 | Synthesis of Trivalent Flexible Frameworks with Ligands Comprising Catechol Units for Functionalizing Surfaces | JUSTUS-LIEBIG-UNIVERSITAT GIESSEN (DE) | 2013-09-19 | — | — | US | disclosed |
| WO-2012032085-A1 | SYNTHESIS OF TRIVALENT FLEXIBLE FRAMEWORKS WITH LIGANDS COMPRISING CATECHOL UNITS FOR FUNCTIONALIZING SURFACES | JUSTUS-LIEBIG-UNIVERSITÄT GIESSEN (DE) | 2012-03-15 | — | — | WO | disclosed |
| WO-2012032084-A1 | SYNTHESIS OF TRIPODAL CATECHOL DERIVATIVES HAVING AN ADAMANTYL BASIC FRAMEWORK FOR FUNCTIONALIZING SURFACES | JUSTUS-LIEBIG-UNIVERSITÄT GIESSEN (DE) | 2012-03-15 | — | — | WO | disclosed |
| EP-2428502-A1 | Synthesis of tripodal catechol derivatives with an adamantyl base for functionalising surfaces | Justus-Liebig-Universität Gießen (DE) | 2012-03-14 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130245270-A1 | Synthesis of Trivalent Flexible Frameworks with Ligands Comprising Catechol Units for Functionalizing Surfaces | CHRM3, CHRM5, CHRM4 | DRD2 375/4885DRD4 198/4885PARP1 1944/4885 |
| US-20130245269-A1 | Synthesis of Tripodal Catechol Derivatives Having an Adamantyl Basic Framework for Functionalizing Surfaces | CHRM1, CHRM5, CHRM4 | DRD2 160/4885DRD4 81/4885PARP1 2050/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.