Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | TSHR | P16473 | 3/20 | 0.36 |
| ▸ | MMP1 | P03956 | 1/20 | 0.34 |
| ▸ | MMP2 | P08253 | 1/20 | 0.34 |
| ▸ | MMP3 | P08254 | 1/20 | 0.34 |
| ▸ | MMP9 | P14780 | 1/20 | 0.34 |
| ▸ | MMP13 | P45452 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 2/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.31 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.31 |
| ▸ | USP2 | O75604 | 1/20 | 0.31 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.31 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7906115 | 0.83 | TSHR (0.41) | LMNAMEN1KMT2ATSHRMAPT | |
| SCHEMBL33568 | 0.81 | MEN1 (0.42) | LMNAMEN1KMT2ATSHRCYP2D6 | |
| SCHEMBL28331743 | 0.81 | LMNA (0.39) | LMNAMEN1KMT2ATSHRCYP2D6 | |
| SCHEMBL28166421 | 0.80 | LMNA (0.42) | LMNAMEN1KMT2ATSHRCYP2D6 | |
| SCHEMBL27607065 | 0.79 | MEN1 (0.41) | LMNAMEN1KMT2ATSHRCYP2D6 | |
| Ammonia Solution, Strong SCHEMBL21219103 | 0.79 | MEN1 (0.41) | LMNAMEN1KMT2ATSHRCYP2D6 | |
| SCHEMBL7373703 | 0.79 | MEN1 (0.38) | LMNAMEN1KMT2ATSHRMAPT | |
| SCHEMBL9515464 | 0.79 | MEN1 (0.38) | LMNAMEN1KMT2ATSHRMAPT | |
| SCHEMBL1972396 | 0.78 | MEN1 (0.39) | LMNAMEN1KMT2ATSHRMAPT | |
| SCHEMBL4002605 | 0.78 | LMNA (0.43) | LMNATSHRCYP2D6MAPTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100172851-A1 | Hydroxy-oligocarboxylic esters: effects on nerve and use for cutaneous and mucocutaneous organs or sites | YU RUEY J | 2010-07-08 | — | — | US | disclosed |
| US-7709014-B2 | Hydroxy-oligocarboxylic esters: effects on nerve and use for cutaneous and mucocutaneous organs or sites | YU RUEY J | 2010-05-04 | — | — | US | disclosed |
| CN-101330911-A | Hydroxy-polycarboxylic acid esters: action on nerves and use on skin and mucocutaneous organs or sites | SCOTT EUGENE J VAN (US) | 2008-12-24 | — | — | CN | disclosed |
| EP-1937246-A2 | HYDROXY-OLIGOCARBOXYLIC ESTERS: EFFECTS ON NERVE AND USE FOR CUTANEOUS AND MUCOCUTANEOUS ORGANS OR SITES | Yu, Ruey J., Dr. (US) | 2008-07-02 | — | — | EP | disclosed |
| WO-2007047486-A2 | HYDROXY-OLIGOCARBOXYLIC ESTERS: EFFECTS ON NERVE AND USE FOR CUTANEOUS AND MUCOCUTANEOUS ORGANS OR SITES | YU RUEY J (US) | 2007-04-26 | — | — | WO | disclosed |
| US-20070093551-A1 | Hydroxy-oligocarboxylic esters: effects on nerve and use for cutaneous and mucocutaneous organs or sites | YU RUEY J | 2007-04-26 | — | — | US | disclosed |