Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 3/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.31 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.31 |
| ▸ | USP2 | O75604 | 1/20 | 0.31 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.31 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | CNR1 | P21554 | 1/20 | 0.31 |
| ▸ | ACHE | P22303 | 1/20 | 0.31 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.31 |
| ▸ | HTR2A | P28223 | 1/20 | 0.31 |
| ▸ | HTR2C | P28335 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3288778 | 0.83 | LMNA (0.38) | TSHRMEN1KMT2ALMNATDP1 | |
| SCHEMBL1972396 | 0.78 | MEN1 (0.39) | TSHRMEN1KMT2ALMNATDP1 | |
| SCHEMBL12138799 | 0.77 | MEN1 (0.38) | TSHRMEN1KMT2ALMNATDP1 | |
| SCHEMBL13043601 | 0.75 | TSHR (0.31) | TSHRNPSR1PIK3CD | |
| SCHEMBL13043590 | 0.75 | TSHR (0.31) | TSHRNPSR1PIK3CD | |
| SCHEMBL28839204 | 0.73 | MEN1 (0.36) | TSHRMEN1KMT2ALMNATDP1 | |
| SCHEMBL448528 | 0.72 | TSHR (0.46) | TSHRMEN1KMT2ALMNATDP1 | |
| SCHEMBL10308621 | 0.71 | ALDH1A1 (0.35) | TDP1ADRA1AALDH1A1PIK3CDHMGCR | |
| SCHEMBL13078567 | 0.71 | ALDH1A1 (0.35) | TDP1ADRA1AALDH1A1PIK3CDHMGCR | |
| SCHEMBL12902749 | 0.71 | ALDH1A1 (0.39) | SMN1; SMN2NPSR1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2000044414-A9 | LUBRICIOUS MEDICAL DEVICES | UNION CARBIDE CHEM PLASTIC (US) | 2001-11-08 | — | — | WO | disclosed |
| EP-1148898-A1 | LUBRICIOUS MEDICAL DEVICES | UNION CARBIDE CHEMICALS & PLASTICS TECHNOLOGY CORPORATION (US) | 2001-10-31 | — | — | EP | disclosed |
| WO-2000044414-A1 | LUBRICIOUS MEDICAL DEVICES | UNION CARBIDE CHEMICALS & PLASTICS TECHNOLOGY CORPORATION (US) | 2000-08-03 | — | — | WO | disclosed |