SCHEMBL328919

SCHEMBL328919

C=C(CCC(N=C=O)N=C=O)C(=O)O

nearest known ligand 0.33

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
TET2 Q6N021 3/20 0.33
TET3 O43151 1/20 0.33
TET1 Q8NFU7 1/20 0.33
GRIK1 P39086 1/20 0.32
GRIK2 Q13002 1/20 0.32
GRM1 Q13255 1/20 0.32
GRM2 Q14416 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4447284 0.81 TET2 (0.31) TET2TET3TET1GRIK1GRIK2
SCHEMBL16353947 0.78
SCHEMBL10709816 0.78
SCHEMBL10336347 0.71 GSTK1 (0.45)
SCHEMBL11043977 0.71 TET2 (0.31) TET2TET3TET1GRIK1GRIK2
SCHEMBL3040262 0.71 TET2 (0.33) TET2TET3TET1GRIK1GRIK2
SCHEMBL4186699 0.69 GSTK1 (0.48)
SCHEMBL2359925 0.69 GRIK1 (0.32) GRIK1GRIK2GRM1GRM2
SCHEMBL1074950 0.69 TET2 (0.46) TET2TET3TET1GRIK1GRIK2
SCHEMBL346413 0.68 TET2 (0.37) TET2TET3TET1GRIK1GRIK2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3280747-A1 METHOD FOR THE SYNTHESIS OF A COPOLYMER CONTAINING IMIDAZOLE PENDANT GROUPS Compagnie Générale des Etablissements Michelin (FR) 2018-02-14 EP disclosed
WO-2016162206-A1 METHOD FOR THE SYNTHESIS OF A COPOLYMER CONTAINING IMIDAZOLE PENDANT GROUPS COMPAGNIE GENERALE DES ETABLISSEMENTS MICHELIN (FR) 2016-10-13 WO disclosed
US-8404144-B2 Compositions including polymerizable bisphosphonic acids and methods 3M INNOVATIVE PROPERTIES COMPANY (US) 2013-03-26 US disclosed
EP-2407142-A1 Use of polymerizable bisphosphonic acids for the treatment of tooth surfaces that are not pretreated with phosphoric acid 3M Innovative Properties Company (US) 2012-01-18 EP disclosed
US-20090075239-A1 COMPOSITIONS INCLUDING POLYMERIZABLE BISPHOSPHONIC ACIDS AND METHODS 3M INNOVATIVE PROPERTIES COMPANY 2009-03-19 US disclosed
US-20090074819-A1 POLYMERIC NANO-SHELLS YISSUM RESEARCH DEVELOPMENT COMPANY OF THE HEBREW UNIVERSITY OF JERUSALEM (IL) 2009-03-19 US disclosed
US-7465758-B2 Dental compositions and methods with arylsulfinate salts 3M INNOVATIVE PROPERTIES COMPANY (US) 2008-12-16 US disclosed
EP-1663115-B1 DENTAL COMPOSITIONS AND METHODS WITH ARYLSULFINATE SALTS 3M INNOVATIVE PROPERTIES CO (US) 2008-09-03 EP disclosed
US-20080014560-A1 DENTAL COMPOSITIONS AND METHODS WITH ARYLSULFINATE SALTS 3M INNOVATIVE PROPERTIES COMPANY 2008-01-17 US disclosed
EP-1819755-A1 POLYMERIC NANO-SHELLS YISSUM RESEARCH DEVELOPMENT COMPANY OF THE HEBREW UNIVERSITY OF JERUSALEM (IL) 2007-08-22 EP disclosed
US-20060105483-A1 Encapsulated light emitting diodes and methods of making 3M INNOVATIVE PROPERTIES COMPANY 2006-05-18 US disclosed
EP-1578377-A1 COMPOSITIONS INCLUDING POLYMERIZABLE BISPHOSPHONIC ACIDS AND METHODS 3M Innovative Properties Company (US) 2005-09-28 EP disclosed
WO-2005034884-A1 DENTAL COMPOSITIONS AND METHODS WITH ARYLSULFINATE SALTS 3M INNOVATIVE PROPERTIES COMPANY (US) 2005-04-21 WO disclosed
US-20050070627-A1 Dental compositions and methods with arylsulfinate salts 3M INNOVATIVE PROPERTIES COMPANY 2005-03-31 US disclosed
US-6818682-B2 Multi-part dental compositions and kits 3M INNOVATIVE PROPERTIES COMPANY 2004-11-16 US disclosed
US-20040206932-A1 Compositions including polymerizable bisphosphonic acids and methods 3M INNOVATIVE PROPERTIES COMPANY 2004-10-21 US disclosed
WO-2004060327-A1 COMPOSITIONS INCLUDING POLYMERIZABLE BISPHOSPHONIC ACIDS AND METHODS 3M INNOVATIVE PROPERTIES COMPANY (US) 2004-07-22 WO disclosed
US-20030018098-A1 MULTI-PART DENTAL COMPOSITIONS AND KITS 3M INNOVATIVE PROPERTIES COMPANY 2003-01-23 US disclosed
WO-2002085313-A1 DENTAL COMPOSITION 3M INNOVATIVE PROPERTIES COMPANY (US) 2002-10-31 WO disclosed
EP-0200589-A1 Adhesive layer used in the manufacture of laminated safety glass, and laminated safety glass containing such a layer SAINT-GOBAIN VITRAGE INTERNATIONAL (FR) 1986-11-05 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080014560-A1 DENTAL COMPOSITIONS AND METHODS WITH ARYLSULFINATE SALTS ARSA, EPN1, SUDS3 TET2 2112/4885TET3 2681/4885TET1 3284/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.