Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR3 | P46089 | 1/20 | 0.41 |
| ▸ | DRD2 | P14416 | 1/20 | 0.39 |
| ▸ | DRD1 | P21728 | 1/20 | 0.39 |
| ▸ | DRD4 | P21917 | 1/20 | 0.39 |
| ▸ | DRD5 | P21918 | 1/20 | 0.39 |
| ▸ | DRD3 | P35462 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | MAPT | P10636 | 3/20 | 0.33 |
| ▸ | IDO1 | P14902 | 2/20 | 0.33 |
| ▸ | TDO2 | P48775 | 1/20 | 0.33 |
| ▸ | PNMT | P11086 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | FTO | Q9C0B1 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 2/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16949487 | 0.84 | GPR3 (0.40) | GPR3DRD2DRD1DRD4DRD5 | |
| SCHEMBL3292309 | 0.70 | GPR3 (0.41) | GPR3DRD2DRD1DRD4DRD5 | |
| SCHEMBL1824700 | 0.69 | MAPK1 (0.38) | ALDH1A1MAPTCYP1A2CYP2D6RAB9A | |
| SCHEMBL21941917 | 0.68 | GPR3 (0.35) | GPR3DRD2DRD1DRD4DRD5 | |
| SCHEMBL1826346 | 0.68 | GRM6 (0.41) | ALDH1A1MAPTNFKB1HSD17B10RAB9A | |
| SCHEMBL1825499 | 0.67 | — | — | |
| SCHEMBL13600308 | 0.67 | GPR3 (0.52) | GPR3DRD2DRD1DRD4DRD5 | |
| SCHEMBL23430324 | 0.67 | GPR3 (0.38) | GPR3ALDH1A1MAPTIDO1TDO2 | |
| SCHEMBL24056381 | 0.67 | GPR3 (0.38) | GPR3ALDH1A1MAPTPNMTRAB9A | |
| SCHEMBL20604090 | 0.67 | GPR3 (0.41) | GPR3DRD2DRD1DRD4DRD5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7723450-B2 | Transition metal compound, ligand system, catalyst system and process for preparing polyolefins | BASELL POLYOLEFINE GMBH (DE) | 2010-05-25 | — | — | US | disclosed |
| US-20070260023-A1 | Transition Metal Compound, Ligand System, Catalyst System and Process for Preparing Polyolefins | BASELL POLYOLEFINE GMBH (DE) | 2007-11-08 | — | — | US | disclosed |
| EP-1761571-A1 | TRANSITION METAL COMPOUND, LIGAND SYSTEM., CATALYST SYSTEM AND PROCESS FOR PREPARING POLYOLEFINS | Basell Polyolefine GmbH (DE) | 2007-03-14 | — | — | EP | disclosed |
| WO-2005118654-A1 | TRANSITION METAL COMPOUND, LIGAND SYSTEM, CATALYST SYSTEM AND PROCESS FOR PREPARING POLYOLEFINS | BASELL POLYOLEFINE GMBH (DE) | 2005-12-15 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070260023-A1 | Transition Metal Compound, Ligand System, Catalyst System and Process for Preparing Polyolefins | ZYX, ZC3HAV1L, ZKSCAN2 | GPR3 3790/4885DRD2 1975/4885DRD1 862/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.