Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM6 | O15303 | 7/20 | 0.41 |
| ▸ | GRM5 | P41594 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 3/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | GAA | P10253 | 3/20 | 0.36 |
| ▸ | MAPT | P10636 | 3/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | LIMK1 | P53667 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | CASP1 | P29466 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1827223 | 0.85 | PTGS2 (0.39) | GRM6GRM5HPGDALDH1A1GAA | |
| SCHEMBL1824700 | 0.77 | MAPK1 (0.38) | GRM6HPGDALDH1A1MAPTKDM4E | |
| SCHEMBL1825499 | 0.73 | — | — | |
| SCHEMBL16996824 | 0.70 | GRM6 (0.52) | GRM6GRM5HPGDALDH1A1GAA | |
| SCHEMBL13713793 | 0.69 | GRM6 (0.47) | GRM6GRM5HPGDALDH1A1GAA | |
| SCHEMBL14190044 | 0.68 | GRM6 (0.50) | GRM6GRM5HPGDALDH1A1GAA | |
| SCHEMBL3289225 | 0.68 | GPR3 (0.41) | HPGDALDH1A1MAPTKDM4ECASP1 | |
| SCHEMBL6019765 | 0.66 | PTGS2 (0.40) | GRM6TP53PTGS2 | |
| SCHEMBL6018836 | 0.64 | PTGS2 (0.39) | GRM6GRM5HPGDALDH1A1GAA | |
| SCHEMBL25289822 | 0.64 | IKBKB (0.38) | HPGDALDH1A1MAPTNPSR1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1854804-B1 | Heterocyclic metallocene compounds and use thereof in catalyst systems for producing olefin polymers | BASELL POLYOLEFINE GMBH (DE) | 2011-05-04 | — | — | EP | disclosed |
| EP-1854804-A1 | Heterocyclic metallocene compounds and use thereof in catalyst systems for producing olefin polymers | Basell Polyolefine GmbH (DE) | 2007-11-14 | — | — | EP | disclosed |
| US-7112638-B2 | Hetero cyclic metallocene compounds and use thereof in catalyst system for producing olefin polymers | BASELL POLYOLEFINE GMBH (DE) | 2006-09-26 | — | — | US | disclosed |
| US-20030036612-A1 | Hetero cyclic metallocene compounds and use thereof in catalyst system for producing olefin polymers | BASELL POLYOLEFINE GMBH (DE) | 2003-02-20 | — | — | US | disclosed |
| EP-1157027-A1 | HETEROCYCLIC METALLOCENE COMPOUNDS AND USE THEREOF IN CATALYST SYSTEMS FOR PRODUCING OLEFIN POLYMERS | Basell Technology Company B.V. (NL) | 2001-11-28 | — | — | EP | disclosed |
| WO-2001047939-A1 | HETEROCYCLIC METALLOCENE COMPOUNDS AND USE THEREOF IN CATALYST SYSTEMS FOR PRODUCING OLEFIN POLYMERS | BASELL TECHNOLOGY COMPANY B.V. (NL) | 2001-07-05 | — | — | WO | disclosed |