Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.37 |
| ▸ | HPGD | P15428 | 5/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.34 |
| ▸ | AKT2 | P31751 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 4/20 | 0.32 |
| ▸ | RAB9A | P51151 | 3/20 | 0.32 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1827223 | 0.86 | PTGS2 (0.39) | MAPK1ALDH1A1HPGDMAPTTDP1 | |
| SCHEMBL6018296 | 0.84 | MAPK1 (0.37) | MAPK1ALDH1A1HPGDMAPTTDP1 | |
| SCHEMBL25245248 | 0.83 | PTGS2 (0.33) | ALDH1A1HPGDMAPTKDM4ENPC1 | |
| SCHEMBL6018873 | 0.81 | PTGS2 (0.34) | ALDH1A1MAPTSMN1; SMN2KDM4ELMNA | |
| SCHEMBL25289822 | 0.81 | IKBKB (0.38) | ALDH1A1HPGDMAPTTDP1SMN1; SMN2 | |
| SCHEMBL5718140 | 0.80 | MAPK1 (0.35) | MAPK1ALDH1A1HPGDMAPTTDP1 | |
| SCHEMBL25244357 | 0.80 | APP (0.41) | ALDH1A1HPGDMAPTKDM4E | |
| SCHEMBL1826346 | 0.77 | GRM6 (0.41) | ALDH1A1HPGDMAPTKDM4ELMNA | |
| SCHEMBL3290015 | 0.74 | ALDH1A1 (0.36) | MAPK1ALDH1A1HPGDMAPTTDP1 | |
| SCHEMBL13337266 | 0.71 | AKT2 (0.46) | MAPK1ALDH1A1HPGDMAPTTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 28 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118290622-A | Metallocene compound, catalyst component for olefin polymerization and catalyst for olefin polymerization comprising the same, and method for producing olefin polymer using catalyst for olefin polymerization | 日本聚乙烯株式会社 | 2024-07-05 | — | — | CN | disclosed |
| CN-113637036-A | Metallocene compound, catalyst component for olefin polymerization, catalyst for olefin polymerization, and process for producing olefin polymer | 日本聚乙烯株式会社 | 2021-11-12 | — | — | CN | disclosed |
| US-20210122856-A1 | METALLOCENE COMPOUND, CATALYST COMPONENT FOR OLEFIN POLYMERIZATION AND CATALYST FOR OLEFIN POLYMERIZATION CONTAINING THE SAME, AND METHOD FOR PRODUCING OLEFIN POLYMER USING CATALYST FOR OLEFIN POLYMERIZATION | JAPAN POLYETHYLENE CORPORATION (JP) | 2021-04-29 | — | — | US | disclosed |
| US-20210122856-A1 | METALLOCENE COMPOUND, CATALYST COMPONENT FOR OLEFIN POLYMERIZATION AND CATALYST FOR OLEFIN POLYMERIZATION CONTAINING THE SAME, AND METHOD FOR PRODUCING OLEFIN POLYMER USING CATALYST FOR OLEFIN POLYMERIZATION | JAPAN POLYETHYLENE CORPORATION (JP) | 2021-04-29 | — | — | US | disclosed |
| US-10919994-B2 | Metallocene compound, catalyst component for olefin polymerization and catalyst for olefin polymerization containing the same, and method for producing olefin polymer using catalyst for olefin polymerization | JAPAN POLYETHYLENE CORPORATION (JP) | 2021-02-16 | — | — | US | disclosed |
| EP-3424937-B1 | METALLOCENE COMPOUND, CATALYST COMPONENT FOR OLEFIN POLYMERIZATION INCLUDING SAME, CATALYST FOR OLEFIN POLYMERIZATION INCLUDING METALLOCENE COMPOUND, AND METHOD FOR PRODUCING OLEFIN POLYMER BY USING CATALYST FOR OLEFIN POLYMERIZATION | JAPAN POLYETHYLENE CORP (JP) | 2020-06-10 | — | — | EP | disclosed |
| US-20190010265-A1 | METALLOCENE COMPOUND, CATALYST COMPONENT FOR OLEFIN POLYMERIZATION AND CATALYST FOR OLEFIN POLYMERIZATION CONTAINING THE SAME, AND METHOD FOR PRODUCING OLEFIN POLYMER USING CATALYST FOR OLEFIN POLYMERIZATION | JAPAN POLYETHYLENE CORPORATION (JP) | 2019-01-10 | — | — | US | disclosed |
| EP-3424937-A1 | METALLOCENE COMPOUND, CATALYST COMPONENT FOR OLEFIN POLYMERIZATION INCLUDING SAME, CATALYST FOR OLEFIN POLYMERIZATION INCLUDING METALLOCENE COMPOUND, AND METHOD FOR PRODUCING OLEFIN POLYMER BY USING CATALYST FOR OLEFIN POLYMERIZATION | Japan Polyethylene Corporation (JP) | 2019-01-09 | — | — | EP | disclosed |
| EP-3056505-B1 | METALLOCENE COMPLEX, PREPARATION METHOD THEREFOR, AND CATALYST COMPOSITION | CHANGCHUN INST APPLIED CHEMISTRY CAS (CN) | 2019-01-02 | — | — | EP | disclosed |
| US-9896519-B2 | Metallocene complex, preparation method thereof and catalyst composition | CHANGCHUN INSTITUTE OF APPLIED CHEMISTRY CHINESE ACADEMY OF SCIENCES (CN) | 2018-02-20 | — | — | US | disclosed |
| EP-1854804-A1 | Heterocyclic metallocene compounds and use thereof in catalyst systems for producing olefin polymers | Basell Polyolefine GmbH (DE) | 2007-11-14 | — | — | EP | disclosed |
| EP-1848748-A1 | PROCESS FOR PREPARING LOW MOLECULAR WEIGHT OLEFIN POLYMERS, ORGANOMETALLIC TRANSITION METAL COMPOUNDS BISCYCLOPENTADIENYL LIGAND SYSTEMS AND CATALYST SYSTEMS | Basell Polyolefine GmbH (DE) | 2007-10-31 | — | — | EP | disclosed |
| US-7112638-B2 | Hetero cyclic metallocene compounds and use thereof in catalyst system for producing olefin polymers | BASELL POLYOLEFINE GMBH (DE) | 2006-09-26 | — | — | US | disclosed |
| WO-2006053757-A1 | PROCESS FOR PREPARING LOW MOLECULAR WEIGHT OLEFIN POLYMERS, ORGANOMETALLIC TRANSITION METAL COMPOUNDS BISCYCLOPENTADIENYL LIGAND SYSTEMS AND CATALYST SYSTEMS | BASELL POLYOLEFINE GMBH (DE) | 2006-05-26 | — | — | WO | disclosed |
| US-20050010039-A1 | Polycyclic fused heteroring compounds metal complexes and polymerization process | GRAF DAVID D (US) | 2005-01-13 | — | — | US | disclosed |
| EP-1487887-A2 | POLYCYCLIC, FUSED HETERORING COMPOUNDS, METAL COMPLEXES AND POLYMERIZATION PROCESS | Dow Global Technologies Inc. (US) | 2004-12-22 | — | — | EP | disclosed |
| WO-2003078480-A2 | POLYCYCLIC, FUSED HETERORING COMPOUNDS, METAL COMPLEXES AND POLYMERIZATION PROCESS | DOW GLOBAL TECHNOLOGIES INC. (US) | 2003-09-25 | — | — | WO | disclosed |
| US-20030036612-A1 | Hetero cyclic metallocene compounds and use thereof in catalyst system for producing olefin polymers | BASELL POLYOLEFINE GMBH (DE) | 2003-02-20 | — | — | US | disclosed |
| EP-1157027-A1 | HETEROCYCLIC METALLOCENE COMPOUNDS AND USE THEREOF IN CATALYST SYSTEMS FOR PRODUCING OLEFIN POLYMERS | Basell Technology Company B.V. (NL) | 2001-11-28 | — | — | EP | disclosed |
| WO-2001047939-A1 | HETEROCYCLIC METALLOCENE COMPOUNDS AND USE THEREOF IN CATALYST SYSTEMS FOR PRODUCING OLEFIN POLYMERS | BASELL TECHNOLOGY COMPANY B.V. (NL) | 2001-07-05 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190010265-A1 | METALLOCENE COMPOUND, CATALYST COMPONENT FOR OLEFIN POLYMERIZATION AND CATALYST FOR OLEFIN POLYMERIZATION CONTAINING THE SAME, AND METHOD FOR PRODUCING OLEFIN POLYMER USING CATALYST FOR OLEFIN POLYMERIZATION | COG1, CPNE4, COG4 | MAPK1 1225/4885ALDH1A1 457/4885HPGD 1593/4885 |
| US-20050010039-A1 | Polycyclic fused heteroring compounds metal complexes and polymerization process | PICALM, AP1M1, PCBP1 | MAPK1 3503/4885ALDH1A1 4081/4885HPGD 3074/4885 |
| US-20210122856-A1 | METALLOCENE COMPOUND, CATALYST COMPONENT FOR OLEFIN POLYMERIZATION AND CATALYST FOR OLEFIN POLYMERIZATION CONTAINING THE SAME, AND METHOD FOR PRODUCING OLEFIN POLYMER USING CATALYST FOR OLEFIN POLYMERIZATION | COG1, CPNE4, COG4 | MAPK1 968/4885ALDH1A1 413/4885HPGD 1719/4885 |
| US-10919994-B2 | Metallocene compound, catalyst component for olefin polymerization and catalyst for olefin polymerization containing the same, and method for producing olefin polymer using catalyst for olefin polymerization | COG1, CPNE4, COG4 | MAPK1 968/4885ALDH1A1 413/4885HPGD 1719/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.