SCHEMBL3289641

SCHEMBL3289641

ClCCCCCCOCc1ccccc1

nearest known ligand 0.54

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 4/20 0.54
TDP1 Q9NUW8 1/20 0.54
TSHR P16473 1/20 0.54
HRH4 Q9H3N8 1/20 0.45
HRH3 Q9Y5N1 1/20 0.45
GBA1 P04062 2/20 0.43
UGCG Q16739 2/20 0.43
GBA2 Q9HCG7 2/20 0.43
EPHX2 P34913 1/20 0.43
NAAA Q02083 2/20 0.42
KCNA3 P22001 2/20 0.41
KCNA5 P22460 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10825883 1.00 L3MBTL1 (0.54) L3MBTL1TDP1TSHRHRH4HRH3
SCHEMBL6941525 1.00 L3MBTL1 (0.54) L3MBTL1TDP1TSHRHRH4HRH3
SCHEMBL10826161 1.00 L3MBTL1 (0.54) L3MBTL1TDP1TSHRHRH4HRH3
SCHEMBL3488296 0.98 TSHR (0.56) L3MBTL1TDP1TSHRHRH4HRH3
SCHEMBL31018369 0.96 L3MBTL1 (0.51) L3MBTL1TDP1TSHRHRH4HRH3
SCHEMBL31018373 0.94 L3MBTL1 (0.50) L3MBTL1TDP1TSHRHRH4HRH3
SCHEMBL1001167 0.92 TSHR (0.58) L3MBTL1TDP1TSHRHRH4HRH3
SCHEMBL14673059 0.91 TSHR (0.48) L3MBTL1TDP1TSHRHRH4HRH3
SCHEMBL14673427 0.91 TSHR (0.48) L3MBTL1TDP1TSHRHRH4HRH3
SCHEMBL14673320 0.91 TSHR (0.48) L3MBTL1TDP1TSHRHRH4HRH3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 36 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5565526-A Functionalized initiators for anionic polymerization FMC CORPORATION (US) 1996-10-15 US claimed
US-10351643-B2 Polymerizable compounds, compositions, polymers, optically anisotropic articles, liquid crystal display devices and organic EL devices DIC CORPORATION (JP) 2019-07-16 US disclosed
US-20170037159-A1 POLYMERIZABLE COMPOUNDS, COMPOSITIONS, POLYMERS, OPTICALLY ANISOTROPIC ARTICLES, LIQUID CRYSTAL DISPLAY DEVICES AND ORGANIC EL DEVICES DIC CORPORATION (JP) 2017-02-09 US disclosed
US-20170037159-A1 POLYMERIZABLE COMPOUNDS, COMPOSITIONS, POLYMERS, OPTICALLY ANISOTROPIC ARTICLES, LIQUID CRYSTAL DISPLAY DEVICES AND ORGANIC EL DEVICES DIC CORPORATION (JP) 2017-02-09 US disclosed
US-7718157-B1 Targeted lipid particles BAKER TERENCE SEWARD 2010-05-18 US disclosed
US-7718157-B1 Targeted lipid particles BAKER TERENCE SEWARD 2010-05-18 US disclosed
US-7531676-B2 Lipids CELLTECH R & D LIMITED (GB) 2009-05-12 US disclosed
US-7531676-B2 Lipids CELLTECH R & D LIMITED (GB) 2009-05-12 US disclosed
EP-0827423-B1 FUNCTIONALIZED CHAIN EXTENDED INITIATORS FOR ANIONIC POLYMERIZATION FMC CORP (US) 2007-12-12 EP disclosed
US-20060148761-A1 Lipids CELLTECH R & D LIMITED 2006-07-06 US disclosed
EP-0873990-A1 BENZOIC ACID COMPOUNDS AND MEDICINAL USE THEREOF YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) 1998-10-28 EP disclosed
EP-0827423-A1 FUNCTIONALIZED CHAIN EXTENDED INITIATORS FOR ANIONIC POLYMERIZATION FMC CORPORATION (US) 1998-03-11 EP disclosed
US-5708092-A Functionalized chain extended initiators for anionic polymerization FMC CORPORATION (US) 1998-01-13 US disclosed
EP-0749466-B1 NOVEL POLYMERISABLE LIQUID-CRYSTALLINE COMPOUNDS BASF AG (DE) 1997-11-12 EP disclosed
US-5654371-A Anionic polymerization process using functionalized initiators FMC CORPORATION (US) 1997-08-05 US disclosed
CN-1143973-A Novel polymerisable liquid-crystalline compounds BASF AG (DE) 1997-02-26 CN disclosed
EP-0749466-A1 NOVEL POLYMERISABLE LIQUID-CRYSTALLINE COMPOUNDS BASF AKTIENGESELLSCHAFT (DE) 1996-12-27 EP disclosed
WO-1996035509-A1 FUNCTIONALIZED CHAIN EXTENDED INITIATORS FOR ANIONIC POLYMERIZATION FMC CORPORATION (US) 1996-11-14 WO disclosed
US-5565526-A Functionalized initiators for anionic polymerization FMC CORPORATION (US) 1996-10-15 US disclosed
WO-1995024454-A1 NOVEL POLYMERISABLE LIQUID-CRYSTALLINE COMPOUNDS BASF AKTIENGESELLSCHAFT (DE) 1995-09-14 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20170037159-A1 POLYMERIZABLE COMPOUNDS, COMPOSITIONS, POLYMERS, OPTICALLY ANISOTROPIC ARTICLES, LIQUID CRYSTAL DISPLAY DEVICES AND ORGANIC EL DEVICES LASP1, ILK, LAS1L L3MBTL1 1288/4885TDP1 2603/4885TSHR 4831/4885
US-20060148761-A1 Lipids PHOSPHO1, FABP7, MBOAT7 L3MBTL1 483/4885TDP1 1253/4885TSHR 2624/4885
US-10351643-B2 Polymerizable compounds, compositions, polymers, optically anisotropic articles, liquid crystal display devices and organic EL devices LASP1, ILK, LAS1L L3MBTL1 1298/4885TDP1 2607/4885TSHR 4833/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.