Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NISCH | Q9Y2I1 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | LCK | P06239 | 1/20 | 0.31 |
| ▸ | KDR | P35968 | 1/20 | 0.31 |
| ▸ | JAK3 | P52333 | 1/20 | 0.31 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.30 |
| ▸ | CASP3 | P42574 | 1/20 | 0.30 |
| ▸ | RAB9A | P51151 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.30 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.30 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21126013 | 0.72 | TSHR (0.43) | NISCHHPGDNPC1CASP3RAB9A | |
| SCHEMBL2964872 | 0.68 | ALDH1A1 (0.35) | NPC1CASP3RAB9ASMN1; SMN2SENP8 | |
| SCHEMBL817896 | 0.66 | — | — | |
| SCHEMBL29776193 | 0.66 | BRD4 (0.35) | NISCHNPC1CASP3RAB9ASMN1; SMN2 | |
| SCHEMBL4314296 | 0.65 | LIMK1 (0.38) | — | |
| SCHEMBL2961338 | 0.61 | BRD4 (0.32) | NPC1CASP3RAB9ASMN1; SMN2SENP8 | |
| SCHEMBL2974370 | 0.61 | ALDH1A1 (0.35) | NPC1CASP3RAB9ASMN1; SMN2SENP8 | |
| SCHEMBL22675051 | 0.61 | HEXA (0.34) | NISCHHPGDMAPK14NPC1CASP3 | |
| SCHEMBL14540297 | 0.61 | LMNA (0.43) | HPGDNPC1CASP3RAB9ASMN1; SMN2 | |
| SCHEMBL1133067 | 0.61 | MYC (0.56) | NPC1CASP3RAB9ASMN1; SMN2SENP8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7723450-B2 | Transition metal compound, ligand system, catalyst system and process for preparing polyolefins | BASELL POLYOLEFINE GMBH (DE) | 2010-05-25 | — | — | US | disclosed |
| US-20070260023-A1 | Transition Metal Compound, Ligand System, Catalyst System and Process for Preparing Polyolefins | BASELL POLYOLEFINE GMBH (DE) | 2007-11-08 | — | — | US | disclosed |
| EP-1761571-A1 | TRANSITION METAL COMPOUND, LIGAND SYSTEM., CATALYST SYSTEM AND PROCESS FOR PREPARING POLYOLEFINS | Basell Polyolefine GmbH (DE) | 2007-03-14 | — | — | EP | disclosed |
| WO-2005118654-A1 | TRANSITION METAL COMPOUND, LIGAND SYSTEM, CATALYST SYSTEM AND PROCESS FOR PREPARING POLYOLEFINS | BASELL POLYOLEFINE GMBH (DE) | 2005-12-15 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070260023-A1 | Transition Metal Compound, Ligand System, Catalyst System and Process for Preparing Polyolefins | ZYX, ZC3HAV1L, ZKSCAN2 | NISCH 2564/4885HPGD 3782/4885LCK 762/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.