SCHEMBL3289745

SCHEMBL3289745

Nc1c(N)c(N)c2ccccc2c1N

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 6/20 0.48
KDM4E B2RXH2 6/20 0.48
HSD17B10 Q99714 5/20 0.48
HPGD P15428 4/20 0.48
SMN1; SMN2 Q16637 4/20 0.48
CASP1 P29466 3/20 0.48
CASP7 P55210 3/20 0.48
TDP1 Q9NUW8 3/20 0.48
ACHE P22303 3/20 0.48
GLA P06280 2/20 0.48
CHRM2 P08172 1/20 0.48
ADRA2A P08913 1/20 0.48
ADORA3 P0DMS8 1/20 0.48
CHRM1 P11229 1/20 0.48
NQO2 P16083 1/20 0.48
MAOA P21397 1/20 0.48
DRD1 P21728 1/20 0.48
SLC6A2 P23975 1/20 0.48
ADRA1A P35348 1/20 0.48
OPRM1 P35372 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30561267 1.00 ALDH1A1 (0.48) ALDH1A1KDM4EHSD17B10HPGDSMN1; SMN2
SCHEMBL743050 0.92 ALDH1A1 (0.48) ALDH1A1KDM4EHSD17B10HPGDSMN1; SMN2
Hydrochloric Acid SCHEMBL11866292 0.89 RAB9A (0.50) ALDH1A1KDM4EHSD17B10HPGDSMN1; SMN2
Hydrochloric Acid SCHEMBL17503334 0.89 RAB9A (0.50) ALDH1A1KDM4EHSD17B10HPGDSMN1; SMN2
SCHEMBL29401594 0.88 ALDH1A1 (0.58) ALDH1A1KDM4EHSD17B10HPGDSMN1; SMN2
SCHEMBL1458501 0.88 ALDH1A1 (0.58) ALDH1A1KDM4EHSD17B10HPGDSMN1; SMN2
SCHEMBL7307237 0.83 KDM4E (0.40) ALDH1A1KDM4EHSD17B10HPGDSMN1; SMN2
SCHEMBL5251509 0.83 KDM4E (0.37) ALDH1A1KDM4EHSD17B10HPGDSMN1; SMN2
SCHEMBL5251516 0.83 ACHE (0.39) ALDH1A1KDM4EHSD17B10HPGDSMN1; SMN2
SCHEMBL21208315 0.79 KDM4E (0.50) ALDH1A1KDM4EHSD17B10HPGDSMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 93 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116948611-A Preparation method of branched epoxy resin pressure-bearing plugging material and oil-based drilling fluid 西南石油大学 2023-10-27 CN claimed
US-11078581-B2 Catalyst composite and method for manufacturing the same UNIST (ULSAN NATIONAL INSTITUTE OF SCIENCE AND TECHNOLOGY) (KR) 2021-08-03 US claimed
US-20200240026-A1 CATALYST COMPOSITE AND METHOD FOR MANUFACTURING THE SAME UNIST (ULSAN NATIONAL INSTITUTE OF SCIENCE AND TECHNOLGY) (KR) 2020-07-30 US claimed
CN-105566628-B A kind of preparation method of the penylene naphtho- Sulfadiazine Compound polymer of 2,5 dihydroxy 1,4 and its fiber 哈尔滨工业大学 2017-10-20 CN claimed
CN-104262171-B A kind of preparation method of 1,4,5,8-tetramino naphthalene stannic chloride hydrochlorate 哈尔滨工业大学 2016-08-24 CN claimed
CN-105820475-A Heat-insulation soundproof floor for high-speed train 江苏润大橡塑材料有限公司 2016-08-03 CN claimed
CN-105623325-A Thick steel-structure fireproof radiation protective paint YUNNAN YOULINSHENG TECH CO LTD 2016-06-01 CN claimed
CN-105566628-A Preparation method of 2,5-dihydroxy-1,4-phenylenenaphtho bipyrimidine polymer and fiber thereof HARBIN INSTITUTE TECHNOLOGY 2016-05-11 CN claimed
CN-105542704-A Flame-retardant high-weather-resistance polysulfide sealant and preparation method thereof SHANGHAI CHUANGYI HOLLOW GLASS MAT CO LTD 2016-05-04 CN claimed
CN-105505289-A High-strength polysulfide waterproof structure adhesive and preparing method thereof SHANGHAI CHUANGYI HOLLOW GLASS MAT CO LTD 2016-04-20 CN claimed
CN-105367976-A Highly-wear-resistant TPE foaming shoe material and preparation method thereof ANHUI XIONGYA PLASTIC TECH CO LTD 2016-03-02 CN claimed
CN-105367975-A High performance TPE cable insulation material and preparation method thereof ANHUI XIONGYA PLASTIC TECH CO LTD 2016-03-02 CN claimed
CN-105255089-A High-fire-retardant high-abrasion-resistant halogen-free cross-linked polyolefin cable insulation material and preparation method thereof LANGFANG CUISHI CABLE MATERIAL CO LTD 2016-01-20 CN claimed
CN-105255090-A Combination composed of SEBS recycled materials and high-strength halogen-free flame-retardant insulating material prepared from combination Jiaxing boer plastic co ltd 2016-01-20 CN claimed
CN-105199292-A High-performance TPE (thermal plastic elastomers) rail transit gasket and preparation method thereof ANHUI XIONGYA PLASTIC TECHNOLOGY CO LTD 2015-12-30 CN claimed
CN-105111658-A Environment-friendly TPE (thermoplastic elastomer) coated toothbrush holder powder with high antibacterial property and strength and preparation method thereof ANHUI XIONGYA PLASTIC TECHNOLOGY CO LTD 2015-12-02 CN claimed
EP-0172427-B1 PROCESS FOR PRODUCTION OF VINYL CHLORIDE POLYMER Shin-Etsu Chemical Co., Ltd. (JP) 1989-07-05 EP claimed
EP-0163825-B1 CROSS-LINKING AGENTS FOR RADIATION CROSS-LINKING FLUOROPOLYMERS Ausimont, U.S.A., Inc. (US) 1988-09-07 EP claimed
EP-0172427-A2 Process for production of vinyl chloride polymer Shin-Etsu Chemical Co., Ltd. (JP) 1986-02-26 EP claimed
EP-0163825-A2 Cross-linking agents for radiation cross-linking fluoropolymers Ausimont, U.S.A., Inc. (US) 1985-12-11 EP claimed