Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | HPGD | P15428 | 3/20 | 0.37 |
| ▸ | MAPT | P10636 | 3/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | GFER | P55789 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3289890 | 1.00 | SMN1; SMN2 (0.43) | SMN1; SMN2ALDH1A1LMNAHPGDMAPT | |
| SCHEMBL16411240 | 1.00 | SMN1; SMN2 (0.43) | SMN1; SMN2ALDH1A1LMNAHPGDMAPT | |
| SCHEMBL3289898 | 0.98 | SMN1; SMN2 (0.44) | SMN1; SMN2ALDH1A1LMNAHPGDMAPT | |
| SCHEMBL3296119 | 0.92 | SMN1; SMN2 (0.46) | SMN1; SMN2ALDH1A1LMNAHPGDMAPT | |
| SCHEMBL11597023 | 0.87 | ALDH1A1 (0.37) | SMN1; SMN2ALDH1A1LMNAHPGDMAPT | |
| SCHEMBL3289759 | 0.84 | — | — | |
| SCHEMBL16411237 | 0.82 | SMN1; SMN2 (0.41) | SMN1; SMN2ALDH1A1LMNAMAPT | |
| SCHEMBL8906298 | 0.79 | LMNA (0.42) | SMN1; SMN2ALDH1A1LMNAHPGDMAPT | |
| SCHEMBL8906308 | 0.79 | LMNA (0.42) | SMN1; SMN2ALDH1A1LMNAHPGDMAPT | |
| SCHEMBL8906193 | 0.77 | LMNA (0.44) | SMN1; SMN2ALDH1A1LMNAHPGDMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7723440-B2 | Functionalized polymers and improved vulcanizates therefrom | BRIDGESTONE CORPORATION (JP) | 2010-05-25 | — | — | US | claimed |
| US-20060178467-A1 | Tire treads with reduced hysteresis loss | BRIDGESTONE CORPORATION (JP) | 2006-08-10 | — | — | US | claimed |
| WO-2018088919-A1 | METHOD FOR PRODUCING MODIFIED POLYDIENES, MODIFIED POLYDIENES PRODUCED THEREBY, AND RUBBER MIXTURES BASED ON THE PRODUCED MODIFIED POLYDIENES | PUBLIC JOINT STOCK COMPANY "SIBUR HOLDING" (RU) | 2018-05-17 | — | — | WO | disclosed |
| US-8207275-B2 | Functionalized polymers and improved vulcanizates therefrom | BRIDGESTONE CORPORATION (JP) | 2012-06-26 | — | — | US | disclosed |
| US-20100298465-A1 | FUNCTIONALIZED POLYMERS AND IMPROVED VULCANIZATES THEREFROM | BRIDGESTONE CORPORATION (JP) | 2010-11-25 | — | — | US | disclosed |
| US-7723440-B2 | Functionalized polymers and improved vulcanizates therefrom | BRIDGESTONE CORPORATION (JP) | 2010-05-25 | — | — | US | disclosed |
| EP-1532179-B1 | FUNCTIONALIZED POLYMERS AND IMPROVED VULCANIZATES THEREFROM | BRIDGESTONE CORP (JP) | 2007-09-19 | — | — | EP | disclosed |
| US-20060178467-A1 | Tire treads with reduced hysteresis loss | BRIDGESTONE CORPORATION (JP) | 2006-08-10 | — | — | US | disclosed |
| US-20060074197-A1 | Functionalized polymers and improved vulcanizates therefrom | BRIDGESTONE CORPORATION (JP) | 2006-04-06 | — | — | US | disclosed |
| EP-1532179-A1 | FUNCTIONALIZED POLYMERS AND IMPROVED VULCANIZATES THEREFROM | Bridgestone Corporation (JP) | 2005-05-25 | — | — | EP | disclosed |
| WO-2004020475-A1 | FUNCTIONALIZED POLYMERS AND IMPROVED VULCANIZATES THEREFROM | BRIDGESTONE CORPORATION (JP) | 2004-03-11 | — | — | WO | disclosed |