Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 3/20 | 0.49 |
| ▸ | SCN10A | Q9Y5Y9 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.45 |
| ▸ | GAA | P10253 | 2/20 | 0.45 |
| ▸ | RXFP1 | Q9HBX9 | 3/20 | 0.44 |
| ▸ | APOB | P04114 | 1/20 | 0.44 |
| ▸ | MTTP | P55157 | 1/20 | 0.44 |
| ▸ | TRPV4 | Q9HBA0 | 3/20 | 0.43 |
| ▸ | IDH2 | P48735 | 1/20 | 0.42 |
| ▸ | CSF1R | P07333 | 1/20 | 0.42 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.42 |
| ▸ | KIT | P10721 | 1/20 | 0.42 |
| ▸ | DDR1 | Q08345 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5144167 | 0.92 | KDM4E (0.48) | EPHX2SCN10AKDM4EGAARXFP1 | |
| SCHEMBL4074915 | 0.91 | APOB (0.51) | EPHX2KDM4EGAAAPOBMTTP | |
| SCHEMBL5145537 | 0.90 | SMN1; SMN2 (0.52) | EPHX2SCN10AKDM4EGAAAPOB | |
| SCHEMBL3289775 | 0.90 | POLB (0.51) | EPHX2SCN10AKDM4EGAARXFP1 | |
| SCHEMBL3295277 | 0.89 | P2RX1 (0.47) | EPHX2SCN10AKDM4EGAA | |
| SCHEMBL3289889 | 0.88 | MAPT (0.45) | EPHX2SCN10AKDM4EGAARXFP1 | |
| SCHEMBL5145637 | 0.87 | F10 (0.48) | SCN10AKDM4EGAARXFP1APOB | |
| SCHEMBL3290068 | 0.86 | EPHX2 (0.45) | EPHX2SCN10ARXFP1APOBMTTP | |
| SCHEMBL4081256 | 0.83 | KDM4E (0.49) | EPHX2KDM4EGAAALDH1A1 | |
| SCHEMBL3292142 | 0.82 | MTTP (0.52) | KDM4EGAAAPOBMTTPALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7723358-B2 | Aroyl-O-piperidine derivatives for the treatment of diabetes-related problems | MERCK PATENT GMBH (DE) | 2010-05-25 | — | — | US | claimed |